Study on synthesis of 5-amino-2,4,6-triiodo-isophthalic acid as medicine intermediate;

The method for synthesis of 2-thiophene ethanol which is an important medicine intermediate was introduced,such as butyl lithium process,Grignard process,natrium reagent process and reduction ester process.

The production technology of triethyl ortho - formate as medicine intermediate is reviewed.

1-(2,3-dichlorophenyl)piperazine is a kind of pharmaceutical intermediate.

During the production process of pharmaceutical intermediates, some by-products that might bring higher value should be fully utilized according to market d.

4-(2,4-Dichlorophenoxy)phenol is a kind of pharmaceutical intermediate, named 2,4-dichloro-4'-hydroxyldiphenylether also.

Improvement of the synthetic process of medical intermediate of 3,4-dihydroxy-5-methoxy methyl benzoate

It has theoretic significance and practical value to synthesize dimenthoxy dicarboxylate biphenyl which is not only a very important medical intermediate but also a new kind of medicament.

The promotion of international competitiveness of pharmaceutical intermediates and active pharmaceutical ingredients industry are very meaningful for the development of pharmaceutical industry.

The actuality of engineering research of pharmaceutical intermediates is studied in this paper.

Applications in synthesization of pharmaceutical intermediates of thiophene were introduced such as thiophene-2-carbaldehyde,2-thiopheneacetic acid,2-(2-thienyl) prop ionic acid,2-thiophene ethanol,2-thiopheneethamine,3-mercaptothiophene,et al.