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1)  DNA strand breaks
DNA链断裂
1.
5) in Beijing on micronucleus formation of Balb/c 3T3 cell and DNA strand breaks, were inspected using cytochalasin B-blocked test and single cell electrophoresis method; and their effects on gap junction intercellular communication (GJIC) of Balb/c 3T3 cells were observed through scrape-loading/dye transfer (SL/DT) technique.
5无机提取物与有机提取物对Balb/c 3T3细胞微核形成与DNA链断裂的影响;通过划痕染料示踪技术(SL/DT)观察PM2。
2.
The results showed that the deoxyguanosine modification and DNA strand breaks upon the concentration of peroxynitrite.
本文采用HPLC-ECD以及琼脂糖凝胶电泳法分别研究了ONOO-诱导的DNA碱基修饰以及DNA链断裂
3.
Objective To investigate DNA strand breaks and micronuclei induced by sodium pentachlorophen (Na-PCP) in different phases and different dosages in vivo.
目的 观察不同剂量五氯酚钠 (Na -PCP)在不同处理后引发小鼠体内免疫细胞的DNA链断裂损伤和微核形成作用。
2)  DNA strand breakage
DNA链断裂
1.
Studies on the DNA strand breakage as biomarker of exposure to aldehyde pollutants;
DNA链断裂作为醛类污染物接触标志物的研究
2.
Study in vitro on the activity of poly(ADP-ribose)polymerase(PARP)and DNA strand breakage induced by nickel;
镍致DNA链断裂及对聚腺苷二磷酸核糖聚酶活性的影响
3.
DNA strand breakage of human hepatoma cells induced by γ-ray measured using the Comet Assay;
彗星分析法检测γ射线诱导的人肝癌细胞DNA链断裂
3)  DNA strand break
DNA链断裂
1.
Objective To observe the DNA strand breaks in HepG2 cell induced by styrene and to evaluate the antagonistic effect of natural cow-bezoar and bilirubin on DNA strand breaks induced by styrene.
目的 观察苯乙烯诱导的人肝癌细胞株 (HepG2 )细胞DNA链断裂损伤以及天然牛黄和胆红素对其损伤的拮抗效应。
2.
Methods DNA strand breaks induced by extractable organic matter of PM10 was assessed by single cell gel electrophoresis(SCGE)assay.
方法单细胞凝胶电泳(SCGE)试验检测细胞DNA链断裂;2\',7\'-二氢二氯荧光素(DCFH)法测定细胞内活性氧水平;免疫组化方法测定8-羟脱氧鸟苷(8-OHdG)在细胞内的表达水平;免疫细胞化学法检测细胞内核转录因子NF-κBp65蛋白表达水平。
4)  DNA double strand break
DNA双链断裂
1.
Objective To investigate the possibility of applying the DNA double strand break and apoptosis of lymphocytes to biological assay in radiation injury.
目的 探讨受照后淋巴细胞DNA双链断裂和凋亡作为放射损伤生物学检测指标的可行性。
2.
Pulsed field gel electrophoresis has been applied to compare the sensitivity of B16 cells and their DNA molecules in the induction of DNA double strand breaks (DSB) by 50 MeV/u 12 C 6+ beam.
用倒转脉冲场凝胶电泳 (PIGE)比较研究了 50 Me V/u1 2 C6 +辐照小鼠 B1 6黑色素瘤细胞及其脱蛋白 DNA分子 ,从而诱导 DNA双链断裂 (DSB)的辐射敏感性。
3.
DNA double strand breaks are important lesions induced by irradiations.
辐射过程引起的生物细胞的DNA双链断裂是一种很重要的细胞损伤过程。
5)  DNA single strand break
DNA单链断裂
1.
0 mg/ml TP could remarkably reduce DNA single strand break induced by 20 GY r-ray.
通过茶多酚(TP)对青、老年NIH小鼠血清中丙二醛(MDA)、红细胞超氧化物歧化酶(SOD)和过氧化氢酶(CAT)活性的作用研究了它对机体自由基的清除功效,并以人体淋巴细胞DNA单链断裂为指标研究了TP对辐射诱发的DNA损伤的保护作用。
2.
Objective To investigate the expression of x ray repair cross complementing group 1 (XRCC1) and DNA single strand break (DNA ssb) and their relation with cerebral ischemia/reperfusion in rats.
目的 观察脑缺血再灌注损伤中XRCC1表达、DNA单链断裂 ,探索它们的关系。
6)  DNA double strand breaks(DS-Bs)
双链DNA断裂
补充资料:主链断裂和主链裂解
分子式:
CAS号:

性质:又称主链断裂和主链裂解。发生在有支链结构高分子的主链上的共价键的断裂反应。可细分为两种类型:一种为主链端基断裂(断裂反应发生在末端链节上);一种为主链无规断裂(高分子主链的断裂没有固定点,主要发生在弱键处)。

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