Naproxen was synthesized from 2 - methoxynaphthalene, using (2R,3R) - dimethyl tartrate as chiral auxiliary, DBDMH and Br2 as brominating agent, KH2PO4 as rearrangement agent, 10% Pd - C/ HCO2NH4 as catalytic transfer hydrogenolytic agent via propionylization, asymmetric bromination, hydrolysis, rearrangement and catalytic tranfer hydrogenolysis.

The Development of Novel Metallocene-based Chiral Ligands and Their Application in Asymmetric Catalysis;

Herein the synthesis and optical resolution of inherently chiral calixarenes and their applications in enantioselective recognition and asymmetric catalysis are reviewed.

A few spiro ligands have been successfully synthesized and applied in asymmetric catalysis.

The ad- vantages and disadvantages of enzyme method,diastereomer derivative method,inducing crystalliza- tion method and asymmetric transformation method are compared.

Based on these results, the asymmetric transformation of DLphydroxyphenylglycine was carried out via formation of salts with (+)lphenylethanesulfonic acid to give optical pure Dphydroxyphenylglycine with 98.

0), and when using acetic acid or acetic acid methanol as solvent the asymmetric transformation.

Study on application of asymmetric hydrogenation by chiral phosphorous ligand catalyst;

Synthesis and Asymmetric Hydrogenation of Novel Cyclic Enamides: (Z)-3-Arylidene-4-acyl-3, 4-dihydro-2H-benzoxazines;

Trans-cyclohexane-backbone iridium complexes with different axial chirality were synthesized from(1R,2S)-2-(pyridin-2-yl)cyclohexanol,and their application in asymmetric hydrogenation of(2H-chromen-3-yl)methanols was investigated.