The concept,developed history and applications in agrochemicals discovery of bioisosterism were reviewed, and many examples of its successful applications were described in this paper.

The applications of the selective patent in new pesticide discovery with examples were briefly reviewed in this paper.

Determination of 33 pesticides in tea by accelerated solvent extraction-gel permeation and solid-phase extraction purification-gas chromatography-mass spectrometry;

Study on zebrafish embryo-toxicity of four pesticides;

Chemistry behavior of pesticides in aquatic environment;

Detection of Biological Toxicity on Drinking Water Polluted by Pesticides;

Novel advances on pesticides degradation by microorganisms;

GC Determination of organophosphorus、 organochlorines and pyrethroids pesticides in tea drinker;

Fumigating Toxicity of Insecticides Commonly Used in Rice Fields to Silkworm,Bombyx mori;

Control effects of insecticides on the main pests of Acacia mearnii;

Considering the negative effects of the traditional insecticide on the environment, health of people, the safety of food and export, it is of great significance to develop innoxious insecticide.

Analysis of agricultural chemicals used in golf links by solid-extract/ HPLC;

Investigation agricultural pollution condition and pollution way which causes as a result of the chemical fertilizer and the agricultural chemicals excessive use,in the pertinent data,in the datafoundation,briefly analyzes the agricultural chemicals,the chemicalfertilizer pollution influence,and proposed the pollution preventingand controlling countermeasure and the measure.