1) TRAIL
[英][treɪl] [美][trel]
肿瘤坏死因子相关凋亡诱导配体
1.
Pentamidine sensitizes leukemia K562 cells to TRAIL-induced apoptosis;
喷他脒增强K562细胞对肿瘤坏死因子相关凋亡诱导配体诱导凋亡敏感性
2.
TRAIL inhibits gastric cancer implanted in nude mice and its relation with death associated protein 3;
肿瘤坏死因子相关凋亡诱导配体对裸鼠胃癌移植瘤的生长抑制作用与死亡相关蛋白3的关系
3.
IFN-γ enhance the ability of the inhibition of TRAIL to neuroblastoma cell line;
干扰素-γ加强肿瘤坏死因子相关凋亡诱导配体抑制神经母细胞瘤细胞的作用
2) tumor necrosis factor-related apoptosis-inducing ligand
肿瘤坏死因子相关凋亡诱导配体
1.
Objective:To explore the anti-tumor effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) against giant cell tumor of bone (GCT), and to study the influence of IFN-γ on the anti-tumor effects of TRAIL and the possible mechanisms.
目的:探讨肿瘤坏死因子相关凋亡诱导配体(tumor necrosis factor-related apoptosis-inducing ligand,TRAIL)对人骨巨细胞瘤(giant cell tumor of bone,GCT)的作用及干扰素-γ(interferon-γ,IFN-γ)对TRAIL抗瘤活性的影响,并探讨其影响机制。
2.
Objective:To observe the effects of different concentrations of glucose on the expression of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL),osteoprotegerin(OPG),and the ligand of osteoprotegerin(OPGL)in osteosarcoma MG63 cells,so as to assess the role of glucose in pathogenesis of diabetic osteoporosis.
目的:观察在不同浓度葡萄糖环境下人成骨肉瘤MG63细胞株肿瘤坏死因子相关凋亡诱导配体(TRAIL)及其护骨素(OPG)、护骨素配体(OPGL)的表达,探讨糖尿病骨质疏松症的发病机制。
3.
Aim: To investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL),cell proliferation and apoptosis in children′s skin hemangioma.
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
3) TNF-related apoptosis-inducing ligand
肿瘤坏死因子相关凋亡诱导配体
1.
Experimental study on apoptosis of osteosarcoma cells induced by TNF-related apoptosis-inducing ligand;
肿瘤坏死因子相关凋亡诱导配体诱导骨肉瘤细胞凋亡的研究
2.
Advance in TNF-related apoptosis-inducing ligand;
肿瘤坏死因子相关凋亡诱导配体研究进展
3.
Although we have known that the expression of death receptors for TNF-related apoptosis-inducing ligand(TRAIL)could be induced on hepatocytes,the effects of hypoxia/reoxygenation(H/R)on TRAIL-mediated apoptosis is unclear.
目的:研究肿瘤坏死因子相关凋亡诱导配体(TNF-related apoptosis-inducing ligand,TRAIL)/死亡受体5(Death receptor 5,DR5)途径在人肝细胞缺氧/再给氧(Hypoxia/reoxygenation,H/R)损伤中的作用,并探讨其作用机制。
5) Tumor necrosis factor-related apoptosis inducing ligand
肿瘤坏死因子相关凋亡诱导配体
1.
Expression of tumor necrosis factor-related apoptosis inducing ligand and its receptors in muscle tissues of experimental autoimmune myositis animal model;
特发性炎性肌病动物模型中肿瘤坏死因子相关凋亡诱导配体及其受体的表达
2.
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
6) Tumor necrosis factor related apoptosis induing ligand gene
肿瘤坏死因子相关凋亡诱导配体基因
补充资料：肿瘤坏死因子
分子式：
CAS号：
性质：又称恶液质素(cachectin)，淋巴毒素(lymphotoxin；LT)。注射卡介苗短小棒状杆菌和酵母多糖等制剂，再以内毒素攻击在小鼠、大鼠和兔等多种动物的血清中出现的一种能引起肿瘤出血性坏死的活性成分。含有唾液酸和半乳糖胺的一种糖蛋白，分子量约150 000。根据其产生来源和结构不同，可分为TNF-α和TNF-β两类，前者有单核-巨噬细胞产生，后者有活化T细胞产生，现已有基因重组技术制备。两类TNF的基本生物活性相似，除具有杀伤肿瘤细胞外，还有免疫调节，参与发热和炎症的发生。大剂量TNF-α可引起恶液质，医疗上可单独或白细胞介素2联合用于治疗肿瘤。
CAS号：
性质：又称恶液质素(cachectin)，淋巴毒素(lymphotoxin；LT)。注射卡介苗短小棒状杆菌和酵母多糖等制剂，再以内毒素攻击在小鼠、大鼠和兔等多种动物的血清中出现的一种能引起肿瘤出血性坏死的活性成分。含有唾液酸和半乳糖胺的一种糖蛋白，分子量约150 000。根据其产生来源和结构不同，可分为TNF-α和TNF-β两类，前者有单核-巨噬细胞产生，后者有活化T细胞产生，现已有基因重组技术制备。两类TNF的基本生物活性相似，除具有杀伤肿瘤细胞外，还有免疫调节，参与发热和炎症的发生。大剂量TNF-α可引起恶液质，医疗上可单独或白细胞介素2联合用于治疗肿瘤。
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参考词条