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1)  Toll-like receptor 4
Toll样受体4
1.
Expression and significance of toll-like receptor 4 by peripheral blood mononuclear cell in rats with adjuvant-induced arthritis;
Toll样受体4在佐剂性关节炎模型大鼠外周血单核细胞中的表达及意义
2.
Expression and significance of Toll-like receptor 4 in distal ileum in rats with acute necrotizing pancreatitis;
急性坏死性胰腺炎时肠道Toll样受体4的表达及其意义
3.
Toll-like receptor 4 in pathogenesis of pulpitis and periapical periodontitis and periodontal disease;
Toll样受体4在牙髓根尖周疾病及牙周病中的作用
2)  Toll Like Receptor 4
Toll样受体4
1.
The effect of Toll like receptor 4 and cytokines on the etiopathogenesis in the rat model with alcoholic liver disease;
Toll样受体4及细胞因子在酒精性肝病发病机理中的作用
2.
Expression of Toll Like Receptor 4 in Kidney of Mice with Lipopolysaccharide Induced Acute Renal Failure;
脂多糖诱导下急性肾功能衰竭小鼠肾脏中TOLL样受体4的表达
3.
Effects of Qinggan Huoxue Recipe and its decomposed formulas on CD14, Toll like receptor 4 and nuclear factor-κB expressed by Kupffer cells;
清肝活血方及其拆方对库普弗细胞表达CD14、Toll样受体4及核因子-κB的影响
3)  TLR4
Toll样受体4
1.
Effect of TLR4 on expressions of p-IRAK1 and p-IκB-α in HPDLCs stimulated by lipopolysaccharide;
Toll样受体4对人牙周膜成纤维细胞表达p-IRAK1和p-IкB-α的影响
2.
Analysis for expression of TLR4 on leucocytes from patients with ankylosing spondylitis and its clinical significance;
Toll样受体4在强直性脊柱炎患者外周血白细胞中的表达及临床意义初探
3.
NE Increases Inflammatory Factors Production by Macrophage Through Modulating TLR4;
去甲肾上腺素通过toll样受体4促进巨噬细胞炎症因子的分泌
4)  Toll-Like Receptor-4
Toll样受体4
1.
In order to investigate the role and significance of Toll-like receptor-4 expression in rats treated by partial intestinal ischemia-reperfusion injury,we observe the change of TLR4 expression level in multiple organs in intestinal ischemia / reperfusion injury rats,and survey the relationship between TLR4 expression level and imflammation factors.
为研究Toll样受体4表达改变在肠缺血再灌注损伤及肠源性多器官功能不全中的作用及意义,我们检测了肠缺血再灌注损伤大鼠各重要脏器的Toll样受体4的表达水平,并观测其与全身炎症反应及多器官功能不全的关系,实验分如下两部分进行: 第一章大鼠小肠缺血再灌注损伤后TLR4基因表达的改变及意义 目的观察大鼠小肠缺血再灌注损伤后小肠组织TLR4的表达及其与炎症因子水平变化的关系。
2.
Objective To determine the expressions of toll-like receptor-4(TLR4)and cytokines in the livers of rats with intrauterine growth retardation(IUGR)and explore the mechanism of increased risk of Gram-negative bacterial infection in IUGR individuals.
目的检测宫内生长受限(IUGR)大鼠肝脏中Toll样受体4(TLR4)及细胞因子的表达,探讨IUGR个体革兰阴性(G-)细菌感染率增加的分子机制。
5)  Toll-like receptor 4
Toll样受体-4
1.
Objective To investigate the expression and significance of Toll-like receptor 4(TLR4)in the uvea of endotoxin in- duced uveitis.
目的探讨Toll样受体-4(TLR4)在内毒素诱导的葡萄膜炎中的表达和意义。
2.
The lipopolysaccharide of Gram-negative bacteria cell wall is the first detective exogenous ligand of the Toll-like receptor 4(TLR-4).
G-细菌细胞壁的脂多糖是第一个被发现的Toll样受体-4(Toll-like receptor4,TLR-4)的外源性配体,TLR-4是人Toll样受体蛋白,属于I型跨膜蛋白,是细菌脂多糖介导的信号跨膜转导的主要受体,对于天然免疫系统识别病原微生物有至关重要的作用。
6)  Toll-like receptor 4
Toll 样受体4
1.
Objective To investigate the effect of Toll-like receptor 4(TLR4) on renin-angiotensin system (RAS) in cardiomyocytes.
目的应用 Toll 样受体4(TLR4)的特异性激动剂脂多糖(LPS)刺激培养的新生大鼠心肌细胞,激活 TLR4介导的信号通路,观察对心肌局部的血管紧张素原和血管紧张素Ⅱ1型受体(AT_1R)表达的影响,探讨TLR4在心血管疾病中的参与机制。
补充资料:5-羟色胺受体阻断剂
分子式:
CAS号:

性质:5-羟色胺(5-HT)是重要的神经递质,也是一种自身活性物质。5-HT通过与靶细胞膜上的5-HT受体结合并诱发生物效应。5-HT受体可分为5-HT1A,5-HT1B,5-HT1C,5-HT2,5-HT3。5-HT受体阻断药大致有以下几类,(1)麦角酸的衍生物如麦解酰二乙胺等;(2)组胺H1受体阻断药如赛庚啶等;(3)吩噻嗪类如氯丙嗪等;(4)肾上腺素α-受体阻断药如酚苄明等。常用于实验室研究、较为特异的5-HT受体阻断剂有麦角苄脂、米安色林、苯噻啶等。

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