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1)  Residual dose
残留剂量
2)  solvent residue
溶剂残留量
1.
Method: The microcapsules prepared with different spray drying parameters have been put in certain surroundings for 12 hours,then the hygroscopic curves were gotten;the mechanism was studied from the following aspects: solvent residue,film's shrink and particle size.
方法:喷雾干燥制成的乌药鞣质微囊置于一定温湿环境中12 h,绘制吸湿曲线以研究进风温度、供液速度、雾化气流速与微囊防潮效果间的规律;并从微囊溶剂残留量、成膜过程膜收缩行为和微囊粒径3个方面研究造成这些规律的机制。
2.
Method The microcapsules prepared with different spray drying parameters have been put in certain surroundings for 12 hours, then the hygroscopic curves were gotten; the mechanism was studied from the following aspects: solvent residue, film’s shrink and particle size.
方法喷雾干燥制成的鞣质微囊置于一定温湿环境中12h,绘制吸湿曲线以研究进风温度、供液速度、雾化气流速与微囊防潮效果间的规律;并从微囊溶剂残留量、成膜过程膜收缩行为和微囊粒径3个方面研究造成这些规律的机理。
3)  residual solvent
溶剂残留量
1.
Determination of residual solvents in fexonadine by capillary gas chromatography;
毛细管气相色谱法测定非索那啶中的溶剂残留量
2.
Determination of the residual solvents in Flucloxacillin Sodium by GC;
气相色谱法测定氟氯西林钠中有机溶剂残留量
4)  residual organic volatile solvents
有机溶剂残留量
1.
Determination of the residual organic volatile solvents in block cream by gas chromatography with headspace sampling;
气相色谱顶空进样法测定防晒霜中有机溶剂残留量
2.
Capillary gas chromatography determination with headspace sampling of the residual organic volatile solvents in flumazenil;
顶空-毛细管气相色谱法测定氟马西尼中有机溶剂残留量
3.
Determination of the residual organic volatile solvents in rifampin and lornoxicam by capillary gas chromatography with headspace sampling;
毛细管气相色谱柱顶空进样法测定利福平及氯诺昔康中有机溶剂残留量
5)  residual solvent
有机溶剂残留量
1.
Determination of three residual solvents in Cefathiamidine;
头孢硫脒中3种有机溶剂残留量的测定
2.
Quantification of residual solvents in cefminox sodium by capillary gas chromatography;
毛细管气相色谱法测定头孢米诺钠中几种有机溶剂残留量
3.
Capillary gas chromatographic determination of residual solvents in chrolobenzylidine;
毛细管气相色谱法测定氯苄律定中几种有机溶剂残留量
6)  residual organic solvent
有机溶剂残留量
1.
Determination of residual organic solvents in biotin by headspace-gas chromatography;
顶空进样毛细管气相色谱法测定生物素中有机溶剂残留量
2.
Analysis of residual organic solvents in cefpirome sulfate by capillary GC with headspace injection;
顶空毛细管GC法测定硫酸头孢匹罗中有机溶剂残留量
3.
The current situation pertaining to the determination of amounts of residual organic solvents in medicinal products is reviewed.
评述了目前药物中有机溶剂残留量测定的状况,以及残留量标准的国际协调方面的进展。
补充资料:卵巢癌的大剂量和超大剂量化疗


卵巢癌的大剂量和超大剂量化疗


  此法系指把化疗的剂量强度提高到一个新的“极限”。主要的理论根据是目前的化疗可达到3~4个对数杀灭,已接近完全杀灭,如再增加几个对数杀灭,就有可能对许多病人达到治愈的疗效。超大剂量化疗则可获得5~7个对数杀灭,并对部分耐药肿瘤细胞有效。在卵巢癌超大剂量化疗时,可增加到第3剂量级,如卡铂为1200~1500mg/m2,环磷酰胺3.5~4.0g/m2,在这样大的剂量时,病人的骨髓抑制毒性很严重,需要支持治疗。支持疗法有①自身骨髓移植;②自身外周血造血干细胞移植和③促粒细胞生长因子应用。目前较易被人接受并且较易施行的支持疗法是自身外周血造血干细胞移植和促粒细胞生长因子的使用。大剂量化疗时,化疗药是常规用药量的2~3倍,骨髓抑制毒性的支持疗法常为促粒细胞生长因子治疗。超大剂量化疗时,化疗药是常规用药量的4~5倍,而骨髓抑制毒性的支持疗法是自身外周血造血干细胞移植和促粒细胞生长因子的联合使用。
  
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