Cilastatin sodiumn could be completely separated from other impurities.

Cilastatin sodium functioning as an inhibitor of DHP- I can enhance the stability of Imipenem and maintain its effective antibiotic concentration in the kidney.

Study on the antagonism of imipenem/cilastatin sodium on endotoxin;

Imipenem/cilastatin Used for Severe Bacterial Infection Patients in Emergency Intensive Care Unit;