1) Liver X receptor
肝X受体
1.
Regulation of macrophage cholesterol efflux and liver X receptor α activation by nicotine;
尼古丁对巨噬细胞肝X受体α表达及胆固醇外流的影响
2.
Effects of liver X receptor agonist on the expressions of C-reactive protein and CD40 ligand and contents of smooth muscle cells in the aorta of ApoE gene knockout mice
肝X受体激动剂对ApoE基因敲除小鼠主动脉壁C-反应蛋白和CD40配体表达及平滑肌细胞含量的影响
2) LXR
肝X受体
1.
Activation of Liver X Receptors (LXRs) Upregulates Fatty Acid Synthase (FAS) Expression in Liver;
肝X受体上调肝脏和肾脏脂肪酸合成酶的表达及机制
2.
METHODS:To activate LXR and increase bile acid synthesis,C57BL/6J mice were fed T0901317 for 7 d and Wistar rats were fed a high-cholesterol diet for 2 wk.
方法:给C57BL/6J小鼠T0901317及给Wistar大鼠饲喂高胆固醇食物,两条途径激活肝X受体(LXR),上调CYP7A1的表达增加胆汁酸的合成后,用全自动生化分析仪测定粪胆汁酸,用RT-PCR的方法测定LXR的下游基因胆汁酸合成限速酶CYP7A1,以及DBP的mRNA水平;用Western Blot测定DBP的蛋白水平;用分光光度法测定DBP活性。
3.
Objective To understand the effect and mechanism of endothelin-1 (ET-1) regulated by liver X receptor (LXR) in vascular endothelial cell line EA.
目的研究肝X受体(liver X receptor,LXR)对血管内皮细胞珠EA。
3) liver X receptors
肝X受体
1.
Peroxisome proliferatoractivated receptors(PPARs)pathway, Liver X receptors(LXR)pathway and Sterol regulatory element binding proteins (SREBPs) pathway are involved in lipid metabolism.
脂代谢信号转导涉及的重要途径包括:过氧化物酶体增殖物激活受体(PPARs)途径、肝X受体(LXR)途径和固醇调节元件结合蛋白(SREBs)途径。
2.
Background Liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily which involve in energy metabolism of intracellular cholesterol and glucose regulation.
背景肝X受体是一种核受体,与细胞内胆固醇及糖等能量代谢有关。
3.
The liver X receptors(LXRs) are the members of the NRs superfamily.
肝X受体(liver X receptors,LXRs)是核受体超家族的成员,一种体内胆固醇感受器,控制着胆固醇的吸收、代谢、转运和分解等过程。
4) liver X receptor α
肝X受体α
1.
Significance and effect of liver X receptor α and sterol regulatory element binding protein-1c in non-alcoholic fatty liver disease in rats;
非酒精性脂肪性肝病大鼠肝X受体α和固醇调节元件结合蛋白-1c的表达及意义
2.
Besides, RT-PCR was applied to detect expression of liver X receptor α (LXRα) and ATP binding cassette transporter A1 (ABCA1) mRNA.
细胞经分组处理24h后,流式细胞仪检测AcLDL聚集量;酶法检测胆固醇和乙酰甘油含量;闪烁计数法检测各组胆固醇流出率,同时分析过氧化物酶体增殖物激活受体γ(PPARγ)抑制剂GW9662预处理对胆固醇流出率的影响(以吡格列酮作为阳性对照);RT-PCR检测肝X受体α(LXRα)和三磷酸腺苷结合盒转运体A1(ABCA1)mRNA表达。
3.
Aim To investigate the mechanism of ezetimibe-induced cholesterol efflux by observing the effect of ezetimibe on ATP binding cassettet transporter A1 and Liver X Receptor α in lipid-loaded cells derived from vascular smooth muscle cell(VSMC).
目的观察依泽替米贝对血管平滑肌源性荷脂细胞三磷酸腺苷结合盒转运体A1和肝X受体α表达的影响,探讨依泽替米贝促进血管平滑肌源性荷脂细胞胆固醇流出的作用机制。
5) liver X receptor
肝脏X受体
6) Liver X receptors (LXR)
肝 X 受体(LXR)
补充资料：肝受体显(成)像
肝受体显(成)像
放射性核素显(成)像方法之一。肝结合蛋白(HBP)仅存于肝细胞，是类血浆糖蛋白NGA的受体，因而肝脏是体内唯一能特异性结合NGA的组织。99mTc-NGA能与肝细胞膜上的肝结合蛋白HBP发生特异性结合，使得肝脏显(成)像。通过肝受体显(成)像不仅可以获得肝脏的放射性影像，而且还能根据HBP的水平评价肝细胞功能。肝受体显(成)像常用的显(成)像剂为99mTc-NGA，显(成)像结果远较肝脏胶体显(成)像清晰，如若采用68Ga-DHGA行PET显(成)像，其分辨率更佳。肝受体显(成)像主要为临床提供一种无创性测定肝细胞储备功能的方法，也可作为肝脏静态显(成)像方法之一。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条