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1)  phenformin [fen'fɔ:min]
苯乙双胍
1.
Detection of phenformin and glyburide illegally mixed into traditional Chinese medicine antidiabetic preparations by the liquid chromatography-mass spectrometry method;
液相色谱-质谱联用法检测中药降糖制剂中非法掺入的苯乙双胍和格列本脲
2.
LC-MS determination of metformin,phenformin,glipizide and glyburide illegally mixed into two kind of antidiabetic Preparations of Traditional Chinese medicine
液相色谱—质谱联用法检测2种中药降糖制剂中非法掺入的二甲双胍、苯乙双胍、格列吡嗪、格列本脲
3.
A high performance liquid chromatographic(HPLC) method was established for the simultaneous determination of four highly polar anti-diabetic drugs,metformin hydrochloride,phenformin hydrochloride,acarbose,and voglibose,in Chinese traditional patent medicines.
建立了测定添加在降糖中成药中高极性的盐酸二甲双胍、盐酸苯乙双胍、阿卡波糖、伏格列波糖等4种化学降糖药物的高效液相色谱方法。
2)  Phenformin [fen'fɔ:min]
盐酸苯乙双胍
1.
Results: Phenformin and glyburide were found in Tangleshu capsule,glyguanid and gliclazide were found in Ketangmin capsule.
目的:进行中药降糖制剂掺入成分盐酸二甲双胍、盐酸苯乙双胍、格列齐特和格列本脲的鉴别。
3)  Phenformin hydrochloride
盐酸苯乙双胍
1.
Determination of phenformin hydrochloride and 1-cyanoguanidine in its tablets by RP-HPLC;
反相高效液相色谱法测定盐酸苯乙双胍片中盐酸苯乙双胍及其有关物质双氰胺的含量
2.
A HPLC-MS/MS method was established for detection of nine anti-diabetic agents——metformin hydrochloride, phenformin hydrochloride, pioglitazone hydrochloride, glipizide, gliclazide, glyburide, glimepiride, gliquidone and nateglinide, which were illegally added in Traditional Chinese Medicines and health care products.
建立了HPLC-MS/MS方法定性检测中药制剂及保健品中违禁添加的盐酸二甲双胍、盐酸苯乙双胍、盐酸吡格列酮、格列吡嗪、格列齐特、格列本脲、格列美脲、格列喹酮、瑞格列奈共9种降糖化学药物。
3.
A HPLC method for determination of metformin hydrochloride, phenformin hydrochloride and glibenclamide in propolis was established.
建立了HPLC检测蜂胶中盐酸二甲双胍、盐酸苯乙双胍和格列本脲的方法,用二极管阵列uv-vis检测器检测,采用柱Diamonsil C18柱,200mm×4。
4)  Phenformin [fen'fɔ:min]
1-苯乙胺双胍
5)  N-(2-Phenylethyl)imi-dodicarbonimidic diamide
1-苯乙胺双胍
6)  PEBG,phenethyl biguanide
苯乙双胍降糖灵
补充资料:苯乙双胍
分子式:C10H15N5
分子量:205.27
CAS号:114-86-3

性质:本品用其盐酸盐(C10H15N5·HCL,[834-28-6]),又称降糖灵,Dibotin,Meltrol,DBI等。盐酸苯乙双胍为白色结晶。熔点175-178β,易溶于水和乙醇,无臭,味苦。

制备方法:由苯乙胺盐酸盐与双氰 胺在142℃左右加热反应,经后处理、精制而得。

用途:本品为降血糖药,以成年型糖尿病的疗效约为88%,适用于各类型的糖尿病。小鼠口服LD50为450mg/kg。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条