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1)  androgen-independent
雄激素非依赖
1.
Establishment of androgen-independent human prostate cancer cell line model LNCaP-AI;
雄激素非依赖性前列腺癌细胞亚系模型LNCaP-AI的建立
2.
Establishment of androgen-independent human prostate cancer line LNCaP by gradual deprivation of hormone;
激素递减法成功建立雄激素非依赖性LNCaP细胞亚系
2)  androgen independent
雄激素非依赖
1.
Objective To construct the prostatic specific promoter used to induce the gene therapy aiming at androgen independent prostatic carcinoma and evaluate the activity.
目的 构建一个前列腺特异性的、可启动针对雄激素非依赖性前列腺癌的基因治疗的改良启动子并测定其活性。
2.
Objectives To construct the prostatic specific promoter used to induce the gene therapy aiming at androgen independent prostatic carcinoma and evaluate the activity.
目的测定本组构建的一个前列腺特异性的、可启动针对雄激素非依赖性前列腺癌的基因治疗的改良启动子rPB-DR的活性。
3)  androgen independent
雄激素非依赖性
1.
Objective:To detect HER-2/neu expression in prostate cancer tissues of both androgen dependent and independent groups and to evaluate the role of HER-2/neu in androgen independent prostate cancer.
目的:检测HER-2/neu基因在雄激素依赖与雄激素非依赖性前列腺癌(PCa)组织中的表达情况,推测这一基因在雄激素非依赖性PCa发生中的意义。
2.
PartⅠ:In vivo Suppression of androgen independent prostate cancer growth by oridonin Objective:To evaluated efficacy oforidonin against DU145 xenografts growth.
在治疗过程中起先对内分泌治疗有效的雄激素依赖性前列腺癌细胞也会慢慢的转变成雄激素非依赖性的细胞,而雄激素非依赖性前列腺癌(AIPCa)的肿瘤细胞对内分泌治疗无效或效果较差,从而导致内分泌治疗失败。
4)  Androgen-independent
雄激素非依赖性
1.
Patients with recurrent prostate cancer may be treated with androgen deprivation strategies,but most cases will eventually develop into androgen-independent prostate cancer(AIPC).
几乎所有一开始对内分泌治疗敏感的前列腺癌最终都将发展成雄激素非依赖性前列腺癌(AIPC)。
2.
The aim was to present our attempts on investigating the pro-apoptosis and growth suppression effects of antiprogestin mifepristone on androgen-independent prostate cancer cell lines LNCaPC 4-2 , PC3 in vitro.
为探讨抗孕激素药米非司酮对雄激素非依赖性前列腺癌细胞株LNCaPC4 2 、PC3的促凋亡及生长抑制作用 ,将不同浓度的米非司酮加入到体外培养的 2株前列腺癌细胞中 ,分别在培养后 3d、5d、7d用SRB染色法检测细胞生长抑制率 ;用流式细胞仪检测加药后 2 4h、48hLNCaPC4 2 和PC3细胞凋亡情况。
3.
We established an androgen-independent prostate cancer cell line induced by the combination of flutamide and androgen-free environment after long-term culture in vivo.
采用氟他胺联合去雄激素环境联合诱导培养的方法在体外建立一株雄激素非依赖性前列腺癌细胞系。
5)  androgen-dependent
雄激素依赖
6)  hormone-independent
非激素依赖
1.
[Objective] To identify the non-steroid transcription factor AP-4 which upregulates the expression of L-plastin in hormone-independent prostate cancer and further elucidate the development mechanism of hormone-refractory prostate cancer.
目的鉴定AP-4是在非激素依赖型前列腺癌中调控L-plastin表达的转录因子,进一步阐明非激素依赖型前列腺癌的发病机制。
补充资料:雄激素与雌激素合用的男用避孕药


雄激素与雌激素合用的男用避孕药


药名。激素类男用避孕药之一。正常男性每天2次口服炔雌醇-3-甲醚20μg和甲基睾丸 酮10mg,于12~18周内达到无精子状态。停药后15周精子数逐渐恢复,35~40周恢复正常水 平。雌激素与孕激素合用的副作用:积贮剂量的雌激素仍可产生乳房增生及其他不良反应。 
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