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1)  thymidine kinase gene
胸苷激酶基因
1.
Cloning and sequencing of the thymidine kinase gene of herpes simplex virus type I strain SM_(44);
单纯疱疹病毒I型SM_(44)株胸苷激酶基因的克隆及序列测定
2.
Methods Thymidine kinase gene of herpes simplex virus (HSV-TK) mediated by adenovirus vector was transferred into HepG2 in vitro followed by ganciclovir (GCV) addition.
目的 :观察腺病毒介导胸苷激酶基因联合抗病毒药物对人肝癌细胞 (HepG2 )的杀伤作用。
3.
Objective To evaluate the toxicity of the herpes simplex thymidine kinase gene(TK ) and ganciclovir(GCV) system in patients with malignant gliomas.
目的探讨和观察单纯疱疹病毒Ⅰ型胸苷激酶基因(TK)逆转录病毒载体生产细胞(PLTKcSN/VPC)结合羟甲基无环鸟苷(GCV)系统治疗(基因治疗)恶性胶质瘤的方法在人体内的安全性。
2)  Thymidine kinase
胸苷激酶基因
1.
The present study reports our efforts in establishing the E1 replicated deficient recombinant adenovirus-mediated thymidine kinase system (Adtk/ACV) and in investigating the suicide effect on rat C6 brain gliomas in vitro and in vivo.
建立缺陷型重组腺病毒载体介导的胸苷激酶基因治疗系统(Adtk/ACV),进行离休和活体治疗大鼠C6脑胶质瘤研究。
3)  human thymidine kinase gene
人胸苷激酶基因
4)  thyimdine kinase(tk) gene
胸苷激酶基因(tk)
5)  thymidine kinase gene(tk)
胸腺核苷激酶基因
6)  Thymidine kinase
胸苷激酶
1.
Adenovirus-mediated herpes simplex virus thymidine kinase gene transfer under the driving of KDR promoter in treatment of experimental human nasopharyngeal carcinoma in nude mice;
腺病毒介导KDR启动子的胸苷激酶基因治疗小鼠人鼻咽癌模型
2.
Influence of inserting glycines on biological properties of HIV Tat-(Gly)_(n)-thymidine kinase fusion proteins;
插入甘氨酸对HIV Tat-胸苷激酶融合蛋白生物学活性的影响
3.
Research on cell killing mechanism of thymidine kinase gene in association with aciclovir;
胸苷激酶基因联合阿昔洛韦对细胞杀伤机制的研究
补充资料:胸苷激酶
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性质:又称胸苷激酶。催化脱氧胸苷磷酸化形成胸苷一磷酸(dTMP):该酶还催化脱氧尿苷磷酸化形成脱氧尿苷一磷酸(dUMP)。正常肝组织内该酶活性很低,在迅速生长的组织如再生肝内酶活性升高,肝恶性肿瘤组织内酶活性明显升高。

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