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1)  endometrial hyperplasia with atypia
子宫内膜非典型增生
1.
Assisted reproductive treatment following conservative management of endometrial hyperplasia with atypia in infertile women;
不孕症合并子宫内膜非典型增生患者助孕治疗的临床分析
2)  atypical hyperplasia of endometrium
子宫内膜不典型增生
1.
Methods A immunohistochemical method of S-P was used to detect Maspin in 67 cases of endometrioid adenocarcinoma,30 cases of atypical hyperplasia of endometrium,and 18 cases of normal endometrium tissue.
目的研究Maspin蛋白在子宫内膜样腺癌和子宫内膜不典型增生组织中的表达及其意义。
3)  atypical hyperplasia of endometria
宫内膜不典型增生
4)  Uterine cervical dysplasia
宫颈非典型增生
5)  endometrial glandular dysplasia
子宫内膜腺体异型增生
1.
Objective:To investigate the clinic pathological and immunophenotypic features of the endometrial glandular dysplasia(EmGD)and the correlation between EmGD and uterine papillary serous adenocarcinoma(UPSC).
目的:研究子宫内膜浆液性乳头状腺癌组织和癌旁组织内子宫内膜腺体异型增生腺体在免疫表型和形态学上的特征和相关性。
6)  endometrial cystohyperplasia
子宫内膜单纯型增生
1.
Methods: The expression of ER and PR in 33 cases of endometrial carcinoma,39 cases of endometrial cystohyperplasia,31 cases of atypical endometrial hyperplasia and 31 cases of normal endometrium in control group were detected by using LSAB immunohistochemical method.
方法:采用LSAB法对33例子宫内膜癌、39例子宫内膜单纯型增生、31例子宫内膜非典型增生及31例正常子宫内膜标本进行ER、PR的检测。
2.
Methods: The expression of K-ras gene in 33 cases of endometrial carcinoma, 39 cases of endometrial cystohyperplasia, 31 cases of atypical endometrial hyperplasia and 31 cases of normal endometrium in control group was detected by using LSAB immunohistochemical method.
方法:采用抗生物蛋白链菌素标记(LSAB)法检测33例子宫内膜癌、31例子宫内膜非典型增生、39例子宫内膜单纯型增生及31例正常子宫内膜标本中Kras癌基因的表达。
补充资料:子宫内膜不典型增生


子宫内膜不典型增生


  子宫内膜不典型增生是子宫内膜癌的癌前病变,长期雌激素的刺激可能是其主要发病因素。其增生限于子宫内膜的腺体,表现为腺体增多,轮廓不规则,间质减少。腺上皮有异型性,表现为细胞排列的极性紊乱或消失,细胞核增大变圆,不规则,核仁明显,胞浆丰富嗜酸性。按病变的程度不同,不典型增生又分为轻、中、重三度。详见附图1~3。子宫内膜不典型增生的发病年龄低于子宫内膜癌。患者常因内分泌失调长期不排卵而生育力低下。月经异常是其突出症状,常表现为阴道不规则出血、月经稀少或闭经一段时间后有长期大量阴道出血。子宫内膜不典型增生的诊断依靠子宫内膜组织病理学检查,但因子宫内膜不典型增生有时表现为散在或单个灶性病变,因此必须取得整个宫腔表面的内膜组织进行诊断,并须与单纯性增生或复合性增生相鉴别。子宫内膜不典型增生的治疗,首先要明确引起雌激素水平升高的原因并进行针对性的治疗,同时根据患者年龄、对生育的要求等用大剂量孕激素、三苯氧胺等药物保守治疗或手术切除子宫。
  
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