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1)  M3 receptor
M3受体
1.
OBJECTIVE To investigate the protective effects of M3 receptor agonist pilocarpine on myocardial ischemia-reperfusion injury in isolated rat hearts.
目的研究M3受体激动剂毛果芸香碱对离体大鼠心肌缺血再灌注损伤的保护作用。
2.
M3 receptor is one of muscarinic receptor subtypes which were classified by the difference of gene expression and pharmacology.
根据M受体的基因表达和药理作用的不同可以分成五种亚型,分别是M1-M5,M3受体是其中的一种。
3.
Objective To observe the effect of activation of M3 receptor on H2O2 induced apoptosis in cultured rat myocytes and to investigate its possible mechanisms.
目的探讨M3受体激动对H2O2诱导的大鼠培养心肌细胞凋亡的作用及其机制。
2)  M_3 receptor
M3受体
1.
Methods Using the acute ischemic model of rats and patch-clamp techniques, the effects of the M_3 receptor on the occurrence of arrhythmias and its possible mechanisms were studied.
目的 研究心脏M3受体 /M3受体介导的钾通道与心律失常的关系,寻找抗心律失常药物的新靶点。
2.
To detect the function and expression of ventricular M_3 receptor(M_3R)in cerebral-cardiac syndrome(CCS)model rats and to explore the relationship between the expression of M_3R and the arrhythmia resulted from CCS,CCS model rats were induced by occluding right middle cerebral artery.
观察M3受体(M3R)在脑心综合征(CCS)模型大鼠心室肌中的作用及其表达,以探讨其与CCS心律失常的关系。
3.
Protective effect of M_3 receptor on H_2O_2-induced apoptosis of rat myocardial cells in vitro;
目的 探讨M3受体激动对H2 O2 诱导的大鼠培养心肌细胞凋亡的作用 ,进一步阐明其机制。
3)  M 3 receptor
M3受体
1.
Objective To observe the effects of M 3 receptor on myocytes injury of rats.
目的 探讨激动M3受体对心肌细胞损伤的保护作用。
4)  anti-M_3 muscarinic receptor autoantibody
M3受体自身抗体
5)  Anti-M3 autoantibody
抗M3受体抗体
6)  M3-receptor antagonist
M3受体阻滞剂
1.
Darifenacin is a selective muscarinic M3-receptor antagonist that has been used in patients with overactive bladder syndrome (OAB).
达非那新是一种选择性M3受体阻滞剂,临床主要用于治疗膀胱过度活动综合征。
补充资料:5-羟色胺受体阻断剂
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性质:5-羟色胺(5-HT)是重要的神经递质,也是一种自身活性物质。5-HT通过与靶细胞膜上的5-HT受体结合并诱发生物效应。5-HT受体可分为5-HT1A,5-HT1B,5-HT1C,5-HT2,5-HT3。5-HT受体阻断药大致有以下几类,(1)麦角酸的衍生物如麦解酰二乙胺等;(2)组胺H1受体阻断药如赛庚啶等;(3)吩噻嗪类如氯丙嗪等;(4)肾上腺素α-受体阻断药如酚苄明等。常用于实验室研究、较为特异的5-HT受体阻断剂有麦角苄脂、米安色林、苯噻啶等。

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