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1)  orexin
食欲素
1.
Orexin neurons in different brain regions exert different roles in regulating reward and motivation in the addiction research: orexin neurons in perifornical area (PFA) and dorsomedial hypothalamus (DMH) are mainly concerned with activating stress system, while orexin neurons in lateral hypot.
下丘脑是调控自然奖赏的重要脑区,它能特异性地表达一种神经肽——食欲素(orexin),这种神经肽在药物奖赏中的作用受到广泛关注。
2.
Orexin is a new kind of neuropeptide found recently that mainly resides in hypothalamus and is produced from the proteolysis of the same precurosor prepro-orexin that is expressed by the specific neurons in lateral hypothalamic area.
Orexin(食欲素)是一类新发现的主要存在于下丘脑的神经肽,它由下丘脑外侧区域特异神经元表达的前体蛋白prepro-orexin经蛋白酶水解衍化而来,包括Orexin-A和Orexin-B两种。
3.
The present study suggests some neural mechanisms underlying the roles of orexins in drug-seeking behavior.
目的:探讨中脑腹侧被盖区(VTA)和伏隔核(NAc)内食欲素Ⅰ型受体在大鼠觅药行为表达中的作用。
2)  Orexins
食欲素
1.
Blood Leptin,Orexins and NPY Levels and Their Relations in Obese Children;
肥胖儿童食欲素、瘦素和神经肽Y水平及其相互关系
2.
Objective:To investigate the changes of concentration of Orexins,Leptin,Insulin in blood among Obese and Normal Children.
目的:探讨儿童肥胖发生中食欲素(Orexins)、瘦素(Leptin)及胰岛素(Insulin)浓度水平变化及相互作用关系。
3.
Methods The concentrations of orexins, leptin, insulin, testosterone(T), estradiol(E_2), luteotrophic hormone(LH), as well as follicle stimulating hormone(FSH) in blood were measured respectively in 78 cases of 13 years old obesity children and 84 normal children as a control group by the means of RIA methods.
方法以78例肥胖的13岁儿童和84例同岁正常对照儿童为研究对象,以放射免疫法测定血中食欲素(orexins)、瘦素(leptin)、胰岛素(insulin)及睾酮(T)、雌二醇(E2)、黄体生成素(LH)、卵泡刺激素(FSH)等浓度,计算骨龄(BA)。
3)  Orexin A
食欲素A
1.
Orexin A and neuropeptide Y levels in plasma and hypothalamus of rats with chronic renal failure;
慢性肾功能衰竭大鼠下丘脑组织和血浆食欲素A及神经肽Y水平的变化及其意义
2.
Objective To examine the changes of expressions of orexin A,orexin receptor-1(OX 1 R),prepro-orexin(Prepro-OX)mRNA,OX 1 R mRNA and ob-R of hypothalamus in rats with chronic renal failure(CRF).
目的探讨大鼠慢性肾衰(CRF)动物模型下丘脑组织食欲素A及其前体mRNA(Prepro-OXmRNA)、食欲素1型受体(OX1R)及其mRNA和瘦素受体(ob-R)表达的变化。
4)  Orexin-A
食欲素A
1.
The impact of Angong Niuhuang Wan(安宫牛黄丸) on orexin-A,Leptin and neuropeptide Y in patients with obstructive sleep apnea-hypopnea syndrome;
安宫牛黄丸对阻塞性睡眠呼吸暂停低通气综合征患者血中食欲素A、瘦素及神经肽Y的影响
2.
Clinical Study on Plasma Orexin-A Levels in Patients with Chronic Obstructive Pulmonary Disease;
慢性阻塞性肺疾病(COPD)患者血浆食欲素A水平的临床研究
5)  orexin
增食欲素
1.
The effect of sibutramine hydrochloride on expression of hypothalamus orexin system gene in high-fat dietary obesity rats;
盐酸西布曲明对高脂肥胖大鼠下丘脑增食欲素系统的影响
2.
Effect of Hypoglycemia on the Orexin and Their Receptors in Rat;
低糖状态对大鼠增食欲素及受体的影响
3.
Abnormal Expression of Prepro-orexin Gene in Rats and Its Relationship with Obesity Development;
大鼠前增食欲素原基因异常表达与肥胖发生的关系
6)  Orexin A
增食欲素A
1.
The Correlation between Nutritional Status and Blood Orexin A,Leptin in Children;
儿童营养状态与血增食欲素A、瘦素的相关性
2.
Objective To explore the change of plasma orexin A concentration and the correlation between plasma orexin A concentration and energy intake in obese children.
目的探讨肥胖儿童血浆增食欲素A水平的改变及其与能量摄入的相关性。
补充资料:紫杉醇 ,紫素,特素,紫烷素,路泰,泰素
药物名称:红豆杉醇

英文名:Taxol

别名: 红豆杉醇;紫杉醇 ,紫素,特素,紫烷素,路泰,泰素
外文名:Taxol ,TAX,Paclitaxel,PTX
适应症: 本品适用于一线或其后的卵巢转移性癌化疗失败以后的治疗。
用量用法:
稀释的泰素注射液应先经过所连接的直径不超过0.22μm孔膜的滤过装置,使用前先用地噻米松、苯海拉明及H2一受体拮抗剂。
注意事项:
1.可有白细胞、血小板减少、贫血(血色素减少)、感染、粘膜炎、出血、过敏反应、低血压、心动过缓、心电图异常、关节痛、肌肉痛、转氨酶和胆红素升高、脱发、恶心及呕吐。 2.对本品有过敏者及骨髓抑制患者忌用。
规格: 浓缩注射液:30mg/支。


类别:抗肿瘤植物成分药
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