Toxicogenetics and toxicogenomics as well as pharmacogenetics explain the genetic basis for the variations of individual response to toxicants by sequencing the human genome and large-scale identification of genome polymorphism.

OBJECTIVE:To investigate status quo of pharmacogenetics of inflammatory bowel disease (IBD), in order to provide some references for rational use of such kinds of drugs in the clinic.

The relationship between pharmacogenetics and drug therapy(including treatment outcome and toxicity),and molecular target therapy of cancer are discussed in this review.

Effccts of α-Glycyrrhizic Acid on Potassium Concentration in Serum of Difference Pharmacogenetic Hartley Guinea Pig;

Effects of genetics variants of pregnant xenobiotic receptor and on pharmacogenetics and drug metabolism;

Along with deep scientific research and continual development of pharmacogenetics and pharmacogenomics,the new era of individual pharmacotherapy will come true in the future.

Pharmacogenomics and pharmacogenetics studies have revealed that genetic poly-morphisms of MDR1 are associated with alteration in P-gp expression and function in different ethnicities and subjects.