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1)  self-emulsifying drug delivery system
自乳化给药系统
1.
AIM:To evaluate the correlation between in vitro release and in vivo absorption of aniracetam in conventional tablets and self-emulsifying drug delivery system(SEDDS),to investigate pharmacokinetics of aniracetam self-emulsifying drug delivery system and conventional tablets of aniracetam after oral administration to rats.
结论:茴拉西坦自乳化给药系统可显著提高药物体内的生物利用度。
2.
Objective To prepare the supersaturatable self-emulsifying drug delivery systems (S-SEDDS) containing Silybin, and to evaluate its basic properties.
目的制备水飞蓟宾过饱和自乳化给药系统(SilybinS-SEDDS),并对其基本性质进行研究。
3.
Objective To prepare the supersaturatable self-emulsifying drug delivery systems(S-SEDDS) containing Silybin,and to evaluate its basic properties.
目的制备水飞蓟宾过饱和自乳化给药系统(Silybin S-SEDDS),并对其基本性质进行研究。
2)  self-microemulsifying drug delivery system
自微乳化给药系统
1.
Preparation of the oral self-microemulsifying drug delivery system of GBE50
银杏酮酯口服自微乳化给药系统的制备
2.
OBJECTIVE To develop the formulation of self-microemulsifying drug delivery system for vinpocetine(VIN-SMEDDS).
目的研究长春西汀自微乳化给药系统(VIN-SMEDDS)的处方工艺。
3.
Self-microemulsifying drug delivery systems(SMEDDS), which are isoreopic mixture of oils, surfactants and/or co-surfactants, can be used for the design of formulation in order to improve the oral absorption of lipophilic drug compounds.
本文分别选择了十一酸睾酮(TU)和水飞蓟素(Silymarin)作为模型药物,制备了两种不同类型的自微乳化给药系统,分别进行了体内外的评价。
3)  SMEDDS
自微乳化给药系统
1.
The development of SMEDDS(self-microemulsifying drug delivery system) in recently years were summeried.
本文综述了近年来自微乳化给药系统(SMEDDS)的研究进展,对自微乳化给药系统的处方优化、质量评价和新型表面活性剂的使用进行了探讨,并对自乳化制剂(SEDDS)在中药新制剂的形成与实际应用进行了展望。
2.
Apart from microemulsion,theself-microemulsifying drug delivery systems,hereinafter referred to as SMEDDS,is mainlycharacterized by its automatic formation of microemulsion under physi.
自微乳化给药系统(self-microemulsifying durgdelivery systems,SMEDDS)除了具有微乳的优点外,其主要特点是在生理条件下能自发形成微乳。
4)  solid self-microemulsion
固体自微乳化给药系统
5)  self-microemulsifying drug delivery system
自微乳给药系统
1.
Release kinetics of oridonin self-microemulsifying drug delivery system in vitro;
冬凌草甲素自微乳给药系统的体外释放动力学研究
6)  self-emulsifying drug delivery system
自乳化释药系统
1.
Formulation optimization of lornoxicam self-emulsifying drug delivery system;
氯诺昔康自乳化释药系统处方优化的研究
2.
Formula optimization of simvastatin self-emulsifying drug delivery system and its pharmacokinetics in Beagle dogs
辛伐他汀自乳化释药系统处方优化及Beagle犬体内药代动力学
3.
Objective:To evaluate the enhancement of self-emulsifying drug delivery system(SEDDS)on the transport of indirubin across the intestinal mucosa of rat and the monolayer of Caco-2 cell,and investigate the pharmcokinetic process of indirubin SEDDS in beagle dogs.
目的:考察靛玉红自乳化释药系统的跨膜转运及其在犬体内的药动学过程。
补充资料:透皮给药系统
分子式:
CAS号:

性质:是一种经皮肤给药的制剂。组成:以硝酸甘油为例,背膜是不透药液的涂铝塑料,中间为药液储库,硝酸甘油吸附在乳糖,胶状二氧化硅上,药液储库的下侧复以控释膜,其表面有一层贴在皮肤上的黏合剂,粘贴皮肤不应引起过敏反应,粘贴层外面有一层铝膜覆盖,在使用时撕去。透皮剂型的优点:避免口服药物在消化道中遇酸酶破坏或食物吸附及消化道功能的影响;无首过代谢;无注射给药的不便;一次用药代替几次用药;药物储库释放持久使半衰期短的药物的药效明显延长;可任意终止给药。透皮剂型的缺点为对皮肤有刺激性或过敏反应;有耐受现象;制作工艺困难,价格昂贵。

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