1)  anthracyclines
蒽环类化疗药物
1.
Objective In order to compare three methods of the renovation in the tissue damage by anthracyclines vascular extravasation.
目的比较蒽环类化疗药物静脉注射外渗后局部组织溃疡修复的三种方法。
2)  anthracycline
蒽环
1.
Study on the Difference between Several Anthracycline Antibiotics Action with DNA by Spectroelectrochemistry;
蒽环类抗肿瘤抗生素与DNA作用差异性的光谱电化学研究
2.
~(99m)Tc-MIBI myocardial perfusion tomography for monitoring the anthracycline cardiotoxicity;
~(99m)Tc-MIBI心肌灌注断层显像监测蒽环类药物的心脏毒性
3.
Objective:To investigate the effect of fructose-1,6-diphosphato (FDP)on myocardial injure induced by anthracycline in children with acute leukemia.
目的:研究1,6-二磷酸果糖(FDP)对使用蒽环类化疗药致心肌损害的白血病患儿的疗效。
3)  Anthracycline
蒽环类
1.
Anthracyclines,paclitaxel and trastuzumab are cardiotoxic during and after the treatment of breast cancer.
在乳腺癌治疗中,蒽环类药物、紫杉类药物和靶向治疗药物曲妥单抗均具有心脏毒性,第三代芳香化酶抑制剂会增加冠状动脉粥样硬化性心脏病(冠心病)的风险,放疗也会引起心脏毒性。
2.
Objective To evaluate the efficacy and toxicity of combined chemotherapy of docetaxel(DOC) combined with cisplatin(DDP) for 28 patients with anthracycline-resistant advanced breast cancer(ABC).
目的观察泰索帝联合顺铂治疗蒽环类耐药性晚期转移性乳腺癌28例的疗效与毒副反应。
3.
Methods: Among 32 patients with advanced breast cancer 18 patients previously received chemotherapy based on anthracycline,while the others did not.
方法:晚期乳腺癌32例其中包括既往应用蒽环类药物治疗18例,非蒽环类药物化疗14例。
4)  Anthracycline
蒽环类药物
1.
In vitro study on Anthracycline-induced injury of cardiomyocyte H9c2;
蒽环类药物心肌损害的体外实验
2.
Recent advances of reactive oxygen species and cytotoxicity of anthracycline on leukemia cells;
蒽环类药物对白血病细胞的细胞毒作用与活性氧的关系研究进展
3.
Clinical Study of Shenmai injection treatment for patients with cardio-toxicity caused by anthracycline;
参麦注射液治疗蒽环类药物所致心脏毒性的临床研究
5)  anthracycline-resistant
蒽环类耐药
1.
Paclitaxel and cisplatin in treatment of anthracycline-resistant advanced breast carcinoma;
紫杉醇联合顺铂治疗30例蒽环类耐药性晚期乳腺癌的疗效分析
2.
Objective To evaluate the efficacy and toxicity of vinorelbine(NVB) plus cisplatin(DDP) in the treatment of anthracycline-resistant advanced breast cancer.
目的观察长春瑞滨(vinorelbine,NVB)联合顺铂(cisplatin,DDP)组成的NP方案治疗蒽环类耐药晚期乳腺癌患者的疗效和毒副反应。
6)  marcellomycin
蒽环类药物
1.
Objective To observe the heart protection effect of parenteral solution Shenqifuzheng in the chemotherapy with marcellomycin.
目的:观察参芪扶正液抗蒽环类药物化疗所致心脏毒性的作用。
参考词条
补充资料:蒽环类抗生素
分子式:
CAS号:

性质:又称蒽环糖苷类抗生素(anthracycline glycoside antibiotics)。基本骨架为7,8,9,10-四氢-5,12-并四苯简称为蒽环酮(an-thracyclinone)的苷元结构,蒽环酮与各种糖以及糖与糖之间苷键连接的不同,组成了结构不同的蒽环类抗生素。多为脂溶性化合物,天然生物发酵过程中产生菌多为放线菌,发酵活性产物在菌丝体内含量为主,经处理后可用有机溶剂提取,进而分离纯化后得到橙红色或黄色晶形粉末。其盐酸盐溶于水和低级醇。分子中的蒽醌为发色团部分,在酸中为红色,碱中呈蓝紫色,常具有指示剂性质,并具有光学活性,水解后可得到蒽环酮和糖的部分。特征紫外吸收峰为235~237nm,255~260nm,290~295nm(甲醇),在450~590nm左右有强而宽的可见光吸收峰。有一定的抗细菌作用,主要有较强的抗肿瘤活性,但多数具有程度不同的毒副作用。到目前为止该类抗生素在临床上有显著抗肿瘤疗效的日渐增多。主要代表有正定霉素(zhengdingmeisu)、阿霉素(adriamycin)、洋红霉素(carminomycin)和阿克拉霉素(aclacinomycin)等。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。