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1)  small-conductance Ca2+-activated K+ channel(SK3)
小电导钙激活的钾通道(SK3)
2)  small conductance Ca 2+ activated potassium channels(SK channels)
小电导的钙激活钾通道
3)  small conductance calcium-activated potassium channel
小电导钙激活型钾通道
4)  large-conductance calcium-activated potassium channel
大电导钙激活钾通道
1.
Effects of atorvastatin on large-conductance calcium-activated potassium channel of arteria mesenterica minor smooth muscle cells in spontaneously hypertensive rats;
阿托伐他汀对自发性高血压大鼠肠系膜动脉平滑肌细胞大电导钙激活钾通道的影响
2.
Aim: To investigate the changes of large-conductance calcium-activated potassium channels(BKCa,MaxiK) during aging and relations between the changes and blood pressure.
目的:探讨大电导钙激活钾通道(BKCa,MaxiK)增龄变化及其与血压水平的关系。
3.
AIM:To observe the effects of valsartan on the large-conductance calcium-activated potassium channel(BKCa)of smooth muscle cells isolated from hypoxia-pulmonary artery hypertension(PAH) rats.
目的:观察缬沙坦对缺氧性肺动脉高压(PAH)大鼠肺动脉平滑肌细胞大电导钙激活钾通道(large-conductance calcium-activated potassiumchannel,BKCa,MaxiK)的影响。
5)  Large-conductance calcium-activated potassium channels
大电导钙激活钾通道
1.
Objective:To study the regulation of Large-conductance calcium-activated potassium channels(BKCa)of mesenteric artery smooth muscle cell by rhynchophylline(Rhy).
目的:探讨钩藤碱(Rhy)对人体肠系膜动脉平滑肌细胞大电导钙激活钾通道(BKCa)的作用。
6)  large-conductance Ca2+-activated potassium channels
大电导钙激活钾通道
1.
The aim of the present study was to examine the effects of tetramethylpyrazine (TMP) on large-conductance Ca2+-activated potassium channels (BKCa channels) in porcine coronary artery smooth muscle cells, in order to provide the experimental evidence for expounding the mechanism of TMP in dilating coronary artery.
采用膜片钳细胞贴附式和内面向外式记录方式观察川芎嗪对猪冠状动脉平滑肌细胞大电导钙激活钾通道(large-conductance Ca2+- activated potassium channels,BKCa channels)的作用,分别用蛋白激酶A(protein kinase A,PKA)抑制剂H-89和蛋白激酶G (protein kinase G,PKG)抑制剂KT-5823处理细胞,再观察川芎嗪对BKCa通道作用的变化。
补充资料:钙离子激活的中性蛋白酶
分子式:
CAS号:

性质:又称钙依蛋白酶(calcium-dependent protease;calpains)。广泛而大量地存在于脊椎动物的各种组织和细胞中。是一种典型的半胱氨酸蛋白酶,其活性绝对需要钙离子,在中性pH值,并有还原剂(如DTT)存在的条件下,其活性最高;而在巯基修饰剂和钙离子螯合剂(如EDTA)存在时,活性降低或丧失。其功能涉及蛋白激酶C的活化,细胞骨架蛋白的水解,其他蛋白激酶的磷酸化,微管蛋白的聚合和解集等。

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