Purification of Flavobacteriun heparinum heparinase I;

Effect of Addition Nucleotides on Heparinase Production by Flavobacterium heparinum;

Expression of Heparinase mRNA and Protein in Malignant Melanoma Lesions as well as A375 Cell Line;

Heparanase:a novel target of tumor metastasis therapy;

Effect of heparanase RNA interference on biological behaviour of HepG2 liver cancer cells;

Prediction and peptide binding assay of HLA-A2.1-restricted CTL epitope from heparanase;

Renal tissue:inflammatory cell infiltration correlated with high expression of heparanase;

Heparanase(Hpa),Matrix Metalloproteinases(MMPs)and Cathepsin D(CathD)are the main enzymes which involve in the degradation of the extracellular matrix(ECM).

Methods Supermotif,quantitative motif and artificial neural network(ANN) were used in the prediction of H-2Kb restricted cytotoxic T lymphocyte(CTL) epitope from amino acid sequence of mouse heparanase.