OBJECTIVE The aim of the present study is to evaluate the effects of the arterial line leukocyte-depleted filter and standard arterial line filter on biochemical and clinical outcome in patients undergoing valve replacement or repair operations using CPB.

Clinical application of white blood cells filter;

Objective To evaluate if routine leukocyte filtration for fresh frozen plasma (FFP) is necessary, so as to provide experimental base for appropriate uses of FFP.

Some studies suggest that leukocyte filtration reduces the ROS mediated lung injury, improves cardiac function and improves the quality of heart and lung transplantation.

Thirty bags of platelet concentrates were detected by platelet and WBC count and bacterial culture before and after leukocyte filtration.

The patients were allocated into a leukocyte depletion group(group LD) and a control group(group C).