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1)  thymidylate synthase inhibitor
胸苷酸合成酶抑制剂
1.
The synergistic effects between DNA methyltransferase inhibitor 5-az acytidine(5-aza-C)and thymidylate synthase inhibitor nolatrexed dihydrochlor ide(Nolatrexed)against LoVo cell and Hep3B cell in vitro were investigated.
通过在体外分别对DNA甲基化转移酶(DNAmethyltransferase,DNMT)抑制剂5-氮杂胞苷(5-azacytidine,5-aza-C)和新型胸苷酸合成酶抑制剂盐酸洛拉曲克(nolatrexeddihydrochloride,Nolatrexed)联合用药于人大肠癌细胞LoVo和人肝癌细胞Hep3B的相互作用性质的观察,探讨DNMT抑制剂和胸苷酸合成酶抑制剂联合用药的可能性。
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2)  thymidylate synthetase inhibitor
胸苷酸合成酶抑制药
3)  Thymidylate synthase
胸苷酸合成酶
1.
Expression of thymidylate synthase and thymidine phosphorylase in gastric cancer and their correlation with prognosis;
胃癌组织中胸苷酸合成酶、胸苷磷酸化酶mRNA表达及其临床意义
2.
Effect of nolatrexed on the thymidylate synthase mRNA expression in three tumor cell lines;
洛拉曲克对3株肿瘤细胞胸苷酸合成酶mRNA水平的影响
3.
Influence of thymidylate synthase on resistance to 5-fluorouracil in colon carcinoma;
胸苷酸合成酶对结肠癌5-FU治疗耐药的影响
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4)  thymidylate synthetase
胸苷酸合成酶
1.
Relationship between genetic polymorphisms of methylene tetrahydrofolate reductase and thymidylate synthetase and chemosensitivity of breast cancer;
亚甲基四氢叶酸还原酶和胸苷酸合成酶基因多态与乳腺癌化疗敏感性关系的研究
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5)  Thymidylate synthase(TS)
胸苷酸合成酶
1.
Objective:To explore whether there is significant difference of Thymidylate synthase(TS)exˉpression in primary and metastatic tumors and to determine that TS levels measured in primary colorectal cancer does not reflect the levels observed in the same patient s metastatic lesions and cannot be used to predict the response of metastatic cancer to chemotherapy.
目的 :研究是否存在大肠原发癌与相应淋巴结转移灶胸苷酸合成酶 (TS)表达水平的差异。
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6)  Thymidylate synthase (TS)
胸苷酸合成酶(TS)
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补充资料：胸苷酸合成酶抑制药
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CAS号：

性质：该类药物可与胸腺嘧啶核苷酸合成酶结合，妨碍2-脱氧尿嘧啶核苷酸与酶结合，使其不能甲基化，影响DNA合成。

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