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1)  Phosphoenolpyruvate carboxykinase
磷酸烯醇丙酮酸羧激酶
1.
Inhibition of phosphoenolpyruvate carboxykinase gene expression by metformin in cultured hepatocytes;
肝细胞中二甲双胍对磷酸烯醇丙酮酸羧激酶基因表达的抑制作用(英文)
2)  phosphoenolpyruvate carboxykinase
磷酸烯醇式丙酮酸羧激酶
1.
Objective To investigate the effects of berberine on mRNA expression levels of hepatic glucokinase (Gck),glucose-6-phosphatase (G6P) and phosphoenolpyruvate carboxykinase (PEPCK) in type 2 diabetic Chinese hamsters and study the molecular mechanisms of action of berberine on glucose metabolism.
目的研究小檗碱对2型糖尿病中国地鼠肝脏葡萄糖激酶(GcK)、葡萄糖-6-磷酸酶(G6P)和磷酸烯醇式丙酮酸羧激酶(PEPCK)mRNA表达的影响,探讨小檗碱影响糖代谢的分子机制。
2.
Objective To evaluate in vitro regulation of phosphoenolpyruvate carboxykinase?(PEPCK?)gene promoter on gene transcription? and construct luciferase reporter plasmid pGL2-PEPCK-Luc.
目的构建磷酸烯醇式丙酮酸羧激酶(PEPCK)基因启动子调控的报告基因表达质粒,为评价PEPCK启动子对下游基因的转录调节创造条件。
3.
The activity of phosphoenolpyruvate carboxykinase, pyruvate kinase, fumarate reductase, malate dehydrogenase, isocitric dehydrogenase and the content of glucose, lactate in Cysticercus Cellulosae during in vivo development were tested.
研究猪囊尾蚴体内发育过程中能量代谢变化规律,应用分光广度法系统地测定了体内发育过程中猪囊尾蚴磷酸烯醇式丙酮酸羧激酶(PEPCK)、丙酮酸激酶(PK)、延胡索酸还原酶(FR)、异柠檬酸脱氢酶(ICD)、苹果酸酶(ME)活性的变化及葡萄糖(GLC)含量、乳酸(LAC)含量的变化。
3)  phosphoenolpyruvate carboxykinase(PEPCK)
磷酸烯醇式丙酮酸羧激酶(PEPCK)
4)  phosphoenolpyruvate carboxykinase (PEPCK)
磷酸烯醇型丙酮酸羧激酶(PEPCK)
5)  PEPCK mRNA
磷酸烯醇式丙酮酸羧激酶mRNA
1.
Effects of NEFA on the expression of PEPCK mRNA and activity of PEPCK in bovine hepatocyte cultivated in vitro
非酯化脂肪酸对体外培养的牛肝细胞中磷酸烯醇式丙酮酸羧激酶mRNA丰度及其活性的影响
6)  PEPCK
磷酸烯醇式丙酮酸激酶
1.
Methods The PEPCK gene was used as a target gene, HPRT, MBP and IgG were used as internal reference, the chromatin immunoprecipitation and PCR were performed with antibody specific for CREB to verify bindings of transcription factor CREB to the PEPCK promoter under various metabolic conditions.
方法以肝脏特异性基因磷酸烯醇式丙酮酸激酶(PEPCK)为待测基因,以IgG和次黄嘌呤鸟嘌呤磷酸核糖基转移酶(HPRT)及髓磷脂基础蛋白(MBP)作为内参基因,采用ChIP验证不同代谢状态下cAMP应答元件结合蛋白(CREB)对PEPCK基因启动子区的结合情况。
补充资料:丙酮酸激酶
分子式:
CAS号:

性质:一种参与糖酵解途径第10步反应的激酶。分子量250 000。由4个亚基(分子量5500)组成。长链脂肪酸、乙酰辅酶A、ATP和丙氨酸对酶活有抑制作用,1,6-二磷酸果糖有活化作用。丙酮酸激酶是一个别构酶。它催化磷酸烯醇式丙酮酸转化而成,同时使ADP磷酸化生成ATP。

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