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1)  TGF-α
TGF-
1.
Different effects of TGF-α and TNF-α on the proliferation and apoptosis of rat and human pheochromocytoma cells;
TGF-α及TNF-α对大鼠和人嗜铬细胞瘤细胞增殖及凋亡的不同作用
2)  TGF-β1
TGF-β_1
1.
Objective By observing the changes of activity of protein kinase A(PKA) in granulation tissue and wound margin tissue of rabbit ear and speed of wound healing after using TGF-β1 to research the mechanism of TGF-β1 effecting.
目的:观察TGF-β_1对兔耳伤口肉芽组织和周边组织蛋白激酶A(Protein Kinase A,PKA)活性及伤口愈合时间的影响,探讨PKA在TGF-β_1影响伤口愈合中的作用。
2.
After the Leydig cells, were infected by Ureaplasma ure-aticum (UU) in vitro, the effect of UU infection on the IL-1 and TGF-β1 secretion by rat Leydig cells was analysed by MTT and ELISA respectively.
体外培养的Leydig细胞经解脲脲原体(UU)感染后,观察其细胞培养上清液中白介素-I(interleukin-1,IL-1)活性(四唑盐比色法即MTT法)和转移生长因子(transforming growth factor-β_1,TGF-β_1)含量(ELISA法)的变化。
3.
Objective To investigate the methods of isolation, cultivation and identification of Adipose derived stem cells (ADSCs) and the feasibility of inducting ADSCs to differentiate to chondrocyte by monolayer culture with exogenous Transforming growth factor-β1 (TGF-β1).
取第3代生长良好的脂肪干细胞,分成两组:一组用含有TGF-β_1的培养基定向诱导培养,另一组为对照组(空白组)用普通培养基继续培养,诱导两周后行Ⅱ型胶原免疫组化染色进行检测鉴定。
3)  TGF-β
TGF-β1
1.
IL-10 and TGF-β1,were simultaneously as.
05];ITP患儿血清中IL-10、TGF-β1的含量也显著低于正常对照组[IL-10:(29。
2.
Objective To study the expression of TGF-β_1 , vimentin and desmin gene in the renal cortex of STZ induced diabetic rats.
目的探讨糖尿病大鼠肾皮质中转化生长因子β1(TGF-β1)、波形蛋白(vimentin)和结蛋白(desmin)表达的变化规律及其相互关系。
3.
During the endoscopic nasal,nasal mucosa were obtained,in which the expression level of Foxp3 were detected by the immunohistochemistry SP and the expression level of IL-10 and TGF-βwere detected by ELISA.
采用免疫组织化学法进行染色检测病例组和对照组Foxp3的表达水平;通过ELISA法检测IL-10和TGF-β1在病例组和对照组的表达情况,最后进行统计学分析。
4)  TGF-β_1
TGF-β1
1.
Significance of hMSH2 and TGF-β_1 protein expression in endomatrial carcinoma;
子宫内膜癌hMSH2及TGF-β1蛋白表达的意义
2.
The Influence of Xuezhikang Associated Aerobic Movement in the Serum of TNF-α and TGF-β_1 of the Non-alcoholic Fatty Liver Patients;
血脂康联合有氧运动治疗对非酒精性脂肪肝患者血清中TNF-α、TGF-β1水平的影响
3.
AIM: To explore the expressions of transforming growth factor-β_1 (TGF-β_1) and transforming growth factor-β receptor Ⅰ(TβRⅠ) in the tissue of the benign biliary stricture and discuss their roles in the process of benign biliary stricture formation.
目的:研究转化生长因子-β1(TGF-β1)、转化生长因子-βⅠ型受体(TβRⅠ)在良性狭窄胆管组织中的表达,探讨其信号转导在良性胆管狭窄形成机制中的作用。
5)  TGF-β_1
TGF-1β
1.
Objective To observe the effects of amniotic membrane on the proliferation and the content of TGF-β_1 in cultured human fibroblasts.
目的观察羊膜对体外培养成纤维细胞的增殖及TGF-1β分泌含量的影响。
2.
After eight weeks of medical treatment,an observation of hepatic fibrosis is carried on by using HE and Masson pigmentation,immunohistochemistry and RT-PCR checking of TGF-β_1,mRNA and protein expression in hepatic tissue.
治疗8周后,用HE和Masson染色观察肝纤维化的形成,免疫组化和RT-PCR检测肝组织中TGF-1βmRNA和蛋白的表达。
6)  TGF-β1
TGF-βl
1.
Objective :To study the expression of Ⅳ-C and TGF-β1proteinin rat with hepatic fibrosis and the therapeutic effects of Bu -Shen-Rou-Gan-Fang (BSRGF) .
结果:补肾柔肝方对肝纤维化有明显的治疗作用,治疗组羟脯氨酸含量要显著低于模型组,同时能使肝组织Ⅳ型胶原和转化生长因子β1(TGF-βl)蛋白表达水平下调。
补充资料:TGF
分子式:
CAS号:

性质:是瘤细胞在生长过程中分泌的一组多肽类物质,因此可从瘤细胞株的培养液中提取它,也可从实体瘤组织中直接提取。TGF能促使瘤细胞自身迅速生长,因为它能与表皮生长因子(EGF)竞争受体,也就是说,肿瘤细胞本身具有结合这类多肽的受体。这就形成了一个阳性反馈系统,即瘤细胞分泌的TGF与瘤细胞自身受体结合,这种结合导致瘤细胞无法控制生长。TGF能使一些非转化指示细胞发生表型转化,生长接触抑制消失,导致在软琼脂上形成集落。TGF分子量6~25kD,依其与EGF竞争膜细胞受体结合点的能力不同及使正常指示细胞表型转化的程度不一,可分为三类:α-TGF, β-TGF及γ-TGF。

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