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1)  replicative adenovirus
肿瘤增殖病毒
2)  conditionally replicating adenovirus
肿瘤增殖型腺病毒
1.
Objective To construct the conditionally replicating adenovirus vector Ad-delE1b55kD-shRNA/Survivin-EGFP that can transfects into HT-29 effectually and selectively and contains shRNA targeting to human Survivin gene.
目的构建特异性强,转染率高,针对人Survivin进行RNA干扰的肿瘤增殖型腺病毒载体(Ad-delE1b55kD-shRNA/Survivin-EGFP)。
2.
Objective To Construct the conditionally replicating adenovirus vector Ad-delE1b55KD-shRNA/Survivin-EGFP which can transfect to HT-29 effectually and selectively and containing shRNA to human Survivin gene.
目的:构建特异性强,转染率高,携带针对人Survivin的shRNA的肿瘤增殖型腺病毒载体,研究其介导的以人Survivin为靶标的RNA干扰对结肠癌细胞株HT-29中Survivin mRNA和蛋白的表达、对结肠癌细胞HT-29增殖和凋亡的影响、时效性及其意义,探讨肿瘤增殖型腺病毒介导RNA干扰对结肠癌的治疗作用。
3)  Tumor-selective replicating virus
肿瘤特异性增殖病毒
4)  replication-competent adenovirus
肿瘤特异增殖型腺病毒
1.
Construction of replication-competent adenovirus shuttle plasmids pAd-delE1b55kD;
肿瘤特异增殖型腺病毒穿梭质粒pAd-delE1b55kD的构建
5)  Tumor proliferation
肿瘤增殖
1.
A Study of hTERT gene expression and tumor proliferation activity as well as their correlation in human gliomas;
端粒酶基因hTERT在脑胶质瘤的表达及与肿瘤增殖相关性的研究
6)  tumorigenic viruses
肿瘤病毒
1.
It was found that the evolutions or changes in pathogenicity and antigenicity of these avian tumorigenic viruses were continuously happening through gene mutations or recombination between viruses.
以家禽肿瘤病毒为对象,曾对生物学的发展有里程碑性的成果。
补充资料:肿瘤病毒

  
  肿瘤病毒
  tumor virus

  导致机体发生肿瘤的病毒。其化学组成、大小、形状等与非肿瘤病毒一样。肿瘤病毒可在动物界中以潜伏状态广泛存在,能在其他因素的共同作用下,诱发肿瘤。比较明确的与病毒有关的肿瘤有白血病、肉瘤、鼻咽癌、乳腺癌、以及宫颈癌等。
  
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