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1)  PDGF-B
血小板源性生长因子-B
1.
Expression of PDGF-B, α-SMA and PCNA of the obstructed kidneys were assessed by immunohistochemistry and the degree of tubulointerstitial damage was scored.
手术后第9d处死各组大鼠,分别经免疫组化方法观察各组大鼠肾组织的血小板源性生长因子-B(PDGF-B)的表达部位、表达水平及α-平滑肌肌动蛋白(α-SMA)、增殖细胞核抗原(PCNA)的表达情况。
2.
Objective To study the effects of PDGF-B and IL-1α on the expression of MMP-1?2 and TIMP-1 in the cultured aorta smooth muscle cells of rats.
目的探讨血小板源性生长因子-B(PDGF-B)与白介素-1α(IL-1α)对动脉平滑肌细胞基质金属蛋白酶(MMP)-1、2及基质金属蛋白酶的组织抑制因子(TIMP)-1表达的影响。
3.
In addition,the results of pathology and the expression of PDGF-B,PDGFR-βand CTGF were observed.
(二)实验研究采用腺嘌呤致大鼠CRF模型,随机分为6组:正常对照组、模型对照组、科素亚组及参芪解毒汤高、中、低剂量组,治疗8周后,测量各组SCr、BUN、TG、CHO、ALB、Hb及血中一氧化氮(NO)、内皮素(ET-1)水平;观察各组大鼠肾脏组织病理学变化以及用免疫组化法检测血小板源性生长因子-B(PDGF-B)、血小板源性生长因子受体-β(PDGFR-β)、结缔组织生长因子(CTGF)在肾组织的表达。
2)  platelet-derived growth factor-B
血小板源性生长因子-B
1.
Objective To transfect the plasmid(EX-A0380-M03) carried human platelet-derived growth factor-B(hPDGF-B) gene into gingival fibroblasts(GFs).
目的用携带人血小板源性生长因子-B (platelet-derived growth factor-B, PDGF-B)基因的真核表达质粒EX-A0380-M03转染Beagle犬牙龈成纤维细胞,复合脱细胞真皮基质(acellular dermal matrix, ADM)体外构建组织工程化复合物,移植修复犬慢性Ⅱ。
2.
Platelet-derived growth factor-B mediates human glomerural mesangial cell extracellular matrix excretion induced by endotelin-1
采用ELISA法测定细胞上清液中IV型胶原(Col IV)、纤维连接蛋白(Fn)的含量;RT-PCR法测定培养系膜细胞内血小板源性生长因子-B(PDGF-B)mRNA的表达,Western blot法检测PDGF-B蛋白的表达。
3)  platelet-derived growth factor-B
血小板源性生长因子B
1.
Level of platelet-derived growth factor-B in plasma and aqueous humor in diabetic retinopathy
糖尿病视网膜病变血浆与房水中血小板源性生长因子B含量的相关研究
2.
Objective: To study the feasibility of transfecting platelet-derived growth factor-B(PDGF-B) gene to bone marrow mesenchymal stem cells(MSCs).
目的:探讨血小板源性生长因子B(PDGF-B)基因转染修饰大鼠骨髓间充质干细胞(MSC)的可行性。
4)  Platelet Derived Growth
血小板源性生长因子-B(PDGF-B)
5)  Platelet Derived Growth Factor-B
血小板源生长因子B
1.
Effects of Qingxuankeli on Aorta Pathology Morphology and Positive Expression of Nuclear Factor-κB, Platelet Derived Growth Factor-B, Basic Fibroblast Growth Factor of Rat;
清眩颗粒对高脂饲料喂养大鼠胸主动脉形态及核因子κB、血小板源生长因子B和碱性成纤维细胞生长因子表达的影响
6)  Platelet derived growth factor
血小板源性生长因子
1.
Expression of platelet derived growth factor in spared dorsal root ganglion after partial dorsal root rhizotomy and the application of acupuncture;
部分背根切断及针刺对备用背根节神经元血小板源性生长因子表达的影响
2.
Characteristics of platelet derived growth factor and its receptors expression in dermal chronic ulcers and their effects on ulcer formation;
血小板源性生长因子和受体在皮肤溃疡中表达特征及其对溃疡形成影响的研究
3.
Changes of vascular endothelial growth factor and platelet derived growth factor in bronchoalveolar lavage fluid of asthmatic rats and the interference effect of valsartan;
哮喘大鼠支气管肺泡灌洗液中血管内皮生长因子和血小板源性生长因子的变化及缬沙坦的干预
补充资料:血小板衍生生长因子
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性质:platelet derired growth factor;PDGF 贮存于血小板α颗粒中的一种碱性蛋白质,是一些细胞,如纤维母细胞、平滑肌细胞、神经胶质细胞的促细胞分裂剂。包括PDGF-I和PDGF-II,二者所含蛋白质相同,仅糖苷含量各异,它们是由两个不同的多肽链由二硫键结合而成的二聚体,其中A链较大(PDGF-I中的A链为17 000,PDGF-II中的A链为15 000),B链较小(14 000)。由血小板纯化得到的PDGF为AB、BB双聚体,许多肿瘤细胞中的PDGF为AA双聚体。目前认为PDGF在伤口愈合、胆固醇与磷酯合成的调节、动脉粥样硬化等多种生理及病理过程中起重要作用。

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