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1)  Nonlinear mixed effect model(NONMEM)
非线性混合效应模型法
1.
Nonlinear mixed effect model(NONMEM) has been widely used in estimating population pharmacokinetics parameters of various drugs.
非线性混合效应模型法广泛应用于临床各类药物的群体药动学参数估算。
2)  Nonlinear mixed effect model
非线性混合效应模型
1.
Estimation of relative clearance of cyclosporin A with nonlinear mixed effect model in kidney transplant patients;
非线性混合效应模型法估算肾移植患者环孢素A的相对清除率
2.
Evaluation of relative bioavailability and pharmacokinetic parameters of ciclosporin preparations by nonlinear mixed effect model;
非线性混合效应模型估算环孢素在人体相对生物利用度和药动学参数
3.
Estimation of relative clearance of cyclosprine A in patients after renal transplantation using nonlinear mixed effect model;
非线性混合效应模型法估算肾移植患者环孢素A清除率
3)  NONMEM
非线性混合效应模型
1.
254 steady-state blood concentrations of TAC after orally administered were evaluated by NONMEM program.
方法:用非线性混合效应模型(NONMEM)程序分析前瞻性收集的22例肝移植患者254份TAC的稳态全血药物浓度样本。
2.
The population pharmacokinetics of MTX was evaluated with NONMEM program and the effects of patients\' age, sex, weight, creatinine clearance rate, blood urea nitrogen and other factors on MTX pharmacokinetic parameters were analyzed quantitatively.
方法:收集皮肤科50例银屑病患者单剂量静脉滴注MTX后稀疏血药浓度数据137个,采用荧光偏振免疫法(FPIA)测定,应用非线性混合效应模型(NONMEM)程序一步法估算MTX的群体药动学参数,并定量分析患者年龄、性别、体质量、肌酐清除率、尿素氮等因素对MTX药动学参数的影响。
3.
The effects of demography and biochemical covariates were investigated by NONMEM.
方法用群体药动学方法,对50名汉、蒙、朝、回、维族健康志愿者的血药浓度进行分析,用非线性混合效应模型(NONMEM)程序建立替硝唑的群体药动学模型,考察人口统计学指标、生化指标等相关因素对药动学参数的影响,并进行模型验证。
4)  nonlinear mixed-effect model
非线性混合效应模型
1.
Methods The model was established by nonlinear mixed-effect model(NONMEM)program using 60 epileptic outpatients with steady-state plasma concentration data and the corresponding demographic data in our hospital.
方法收集我院门诊60名癫痫患者丙戊酸钠稳态血药浓度监测数据和相应的人口学数据,应用非线性混合效应模型(non linearm ixed-effectmodel,NONMEM)程序对收集的数据进行分析,建立群体药动学模型。
2.
The paper describes the problem of conventional growth and yield model and the use of nonlinear mixed-effect models in modeling basal area.
该文描述了传统生长收获模型存在的问题及非线性混合效应模型在预估林分断面积方面的应用,介绍了非线性混合效应模型的表达形式。
5)  linear mixed effects model
线性混合效应模型
1.
According the characteristics of the bivariate repeated measurement data,using the MIXED procedure of SAS software to fit linear mixed effects model.
为了探讨环境医学研究中不满足独立性要求资料相关性分析的方法,针对双反应变量重复测量资料的特点,采用SAS软件的MIXED过程,建立线性混合效应模型。
6)  generalized linear mixed models
广义线性混合效应模型
1.
Objective :To discuss generalized linear mixed models(GLMMs) of categorical repeated measurement datas in clinical curative effect evaluation,implementing with GLIMMIX macro in SAS8.
目的:探讨临床疗效评价中分类重复测量资料的广义线性混合效应模型(GLMMs)及SAS8。
补充资料:非线性光学效应
分子式:
CAS号:

性质:指由电磁辐射所产生,但其响应却与照度不成比例的一种现象。光化学中重要的非线性光学效应有谐频发生、激光、拉曼位移等。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条