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1)  compound fluorouracil and dimethysulfoxy solution
复方氟脲嘧啶二甲亚砜溶液
2)  Compound injection of Polyphase Liposome of 5-Fluorouracil
复方氟脲嘧啶脂质体
1.
The test group was treated mainly with Compound injection of Polyphase Liposome of 5-Fluorouracil or with DDP for more than two cycles.
目的 观察复方氟脲嘧啶脂质体治疗晚期消化系统肿瘤的临床疗效及毒副反应。
3)  sulfamonomethoxine compound-ofloxacin injection
复方磺胺间甲氧嘧啶-氧氟沙星注射液
4)  fluorouracil [英][,flu:ərəu'jurəsil]  [美][,flʊro'jʊrəsɪl, ,flɔr-, ,flor-]
氟脲嘧啶
1.
Bovin serum albumin microspheres containing 5-fluorouracil(FU-BM) were prepared by emulsion-direct heat stabilization technique.
目的:探讨以牛血清白蛋白为载体的氟脲嘧啶白蛋白微球的最佳制备方法及有关体外性质。
2.
Objective To explore the efficacy and safety of FOLFOX4 regimen including oxaliplatin(L-OHP),fluorouracil(5-Fu) and calcium folinate(CF) as therapy for patients with advanced gastric cancer.
目的观察奥沙利铂(L-OHP)联合氟脲嘧啶(5-Fu)、亚叶酸钙(CF)组成的FOLFOX4方案治疗晚期胃癌的近期疗效和毒副反应。
3.
Objective To study the effect and toxicity of the regimen of Oxaliplatin combined with Fluorouracil and Leucovorin in the treatment of advanced colorectal Cancer.
目的观察奥沙利铂(L-OHP)联合氟脲嘧啶(5-Fu)及亚叶酸钙(CF)治疗晚期大肠癌的疗效和不良反应。
5)  5-Fluorouracil
氟脲嘧啶
1.
Oxaliplatin Combined with 5-Fluorouracil for Advanced Gastric Carcinoma:a Report of 42 Cases;
奥沙利铂联合氟脲嘧啶治疗晚期胃癌42例临床观察
2.
Clinical Observation of Late Stage Gastrointestinal Tumor Patients Treated Principally by Compound Injection of Polyphase Liposome of 5-Fluorouracil;
复方氟脲嘧啶脂质体治疗晚期消化系统肿瘤的疗效观察
3.
Objective To evaluate the efficacy and toxicity of weekly paclitaxel(PTX) combined with 5-fluorouracil(5-Fu),DDP and CF as alternative chemotherapy for patients with advanced esophageal carcinoma.
目的评价周剂量紫杉醇(PTX)联合氟脲嘧啶(5-Fu)、顺铂(DDP)和醛氢叶酸(CF)组成PLFP方案治疗晚期食管癌的临床疗效和毒副反应。
6)  5-Fu
氟脲嘧啶
1.
Clinical observation of oxaliplatin combined with leucovorin and 5-Fu in advanced gastric carcinoma;
草酸铂联合亚叶酸钙氟脲嘧啶治疗晚期胃癌的临床观察
2.
Tissue Penetration of Capecitabine and Its Tumor-Selective Delivery of 5-FU in Advanced Breast Cancer Patients;
卡培他滨乳腺组织穿透及向氟脲嘧啶转化的药动学研究(英文)
3.
Pharmacokinetic analysis on the tissue penetration of capecitabine and tumor selective distribution of 5-FU in patients with advanced breast cancer;
卡培他滨乳腺组织穿透及向氟脲嘧啶转化的药动学研究
补充资料:二氟脲
分子式:C14H9ClF2N2O2
分子量:310.68
CAS号:35367-38-5

性质:除虫脲纯品为白色结晶,熔点230-232℃。原药(有效成分含量95%)外观为白色至浅黄色结晶粉末,比重1.56,熔点210-230℃。20℃时在水中溶解度为0.1mg/L,丙酮中6.5g/L,易溶于极性溶剂如乙腈、二甲基砜,也可溶于一般极性溶剂如乙酸乙酯、二氯甲烷、乙醇。制剂由25%除虫脲及湿润剂、分散剂、惰性填料组成。外观为白色至浅黄色粉末,比重约0.4,悬浮率不低于60%,常温贮存稳定性最少2年。

制备方法:将2,6-二氟苯甲酰胺和4-氯苯基异氰酸酯置于二甲苯中加热回流,反应完成后冷却,所得结晶物用二甲苯洗涤、干燥而得伏虫脲。

用途:伏虫脲是一种新杀虫剂,对许多重要害虫的幼虫具有胃毒作用。它通过干扰表皮沉积作用,使昆虫不能正常蜕皮或变态而死亡。也可抑制昆虫卵内胚胎发育过程中的表皮形成,使卵不能正常发育孵化,同时对昆虫的生殖力也有一定的抑制作用。该品杀虫谱广,特别是对鳞翅目幼虫的效果尤为明显。由于其特有的作用机制,对人畜低毒,对天敌危害性小,是近年来发展的比较好的选择性杀虫剂。

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