1)  Newborn
致畸因素
2)  Teratogenicity
致畸
1.
Thirty days feeding experiment of SD rats with die fary fibre from Eucheuma and the teratogenicity;
麒麟菜膳食纤维对SD大鼠30天喂养实验和致畸作用
2.
Study on mutagenicity and teratogenicity of Chanhoukangfunning in mice;
产后康复宁的致突变、致畸试验研究
3.
The authors studied some of the reproductive and developmental toxicity on Plant Mineral Elements(PME) by Teratogenicity Test.
利用传统致畸试验方法对植物活力素 ( PME)进行了部分的生殖与发育毒性实验。
3)  malformation
致畸
1.
Application of analytical technique for fish canceration, malformation and mutation in fisheries environmental monitoring;
鱼类“致癌、致畸、致突变”测试技术在渔业环境监测中的应用
2.
Methods Collect all studies that have been published in the world with regard to malformation on LTG monotherapy during pregnancy .
方法 收集已公开发表的关于女性妊娠期包含LTG单药治疗癫痫致畸率的临床试验或调查研究,按照试验设计和meta分析的要求,进行筛选,对合格试验进行meta分析,从而计算妊娠期LTG单药治疗癫痫致畸率相对正常人群畸胎率的优势比(odds ratio,OR),为药物的妊娠毒性提供证据。
4)  teratogenesis
致畸
1.
Teratogenesis caused by passive smoking on embryo and the establishment of a good animal model.;
被动吸烟对胚胎致畸作用的研究和致畸动物模型的建立
2.
Effect of Quanjia Yangshen Jiaonang on the teratogenesis and tumoricidal action of cyclophosphamide;
全甲洋参胶囊对环磷酰胺致畸和抑瘤作用的影响
3.
Objective:To study the effect of dietary supplementation of folic acid(FA),VC,VB 6 and taurine on teratogenesis of rats induced by cyclophosphamide.
结论 叶酸有明显的促进胚胎发育和拮抗环磷酰胺致畸的作用 ,且与 VC、VB6及牛磺酸联合应用的效果明显优于单独补充。
5)  teratogenicity
致畸毒性
1.
BACKGROUND AND AIM:To study teratogenicity of glycosides of chaenomeles speciossa(GCS)on ICR mice during the sensitive period.
背景与目的:评价木瓜苷对ICR小鼠的胚胎毒性和致畸毒性,为其临床应用提供毒理学依据。
6)  teratogenesis
致畸作用
1.
Investigation on the teratogenesis from Eucommia Bark, Baikal Skullcap and Ramie root by using Hydra regeneration assay;
应用水螅再生试验初探杜仲等中药的致畸作用
2.
Retinoic acid can induce teratogenesis of the fetus of many animals including human,and its biological activities are induced by a serious of different retinoic acid accepters and their ligands.
视黄类受体基因突变和不同视黄类受体及其配体与致畸作用的关系,以及此类受体对其它基因表达的调节作简要综述。
参考词条
补充资料:致畸
分子式:
CAS号:

性质:又称致畸。指干扰子宫内胚胎或胎儿正常发育,使新生儿异常率明显增高的一型特殊毒性作用。干扰胚胎发生过程对致畸的最终表达具有重要意义。胚胎发生的各个顺序过程及其相互关系易被外来物质干扰或破坏。器官发生期对接触致畸原最为敏感,可致肉眼可见的结构畸形;畸形也可发生在受精至胚胎发生期。对人的敏感期是受孕第3周至第3个月。胎儿发育晚期,如增殖期对致畸作用相对不敏感,通常出现“全或无”型反应,如死亡或无肉眼的变化。致畸作用所致发育异常的结局是死亡、畸形、生长延缓及功能障碍。

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