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1)  drug delivery
药物控缓释
1.
The new drug delivery systems should keep the drug at a desired therapeutic level in the body while avoiding the need for frequent administration.
该文对功能高分子在新型给药系统中的应用及研究进展进行了评述;结合具体药物剂型,针对不同给药系统的特点和实际需要以及功能高分子的相关特性,讨论了功能高分子材料在药物控缓释中的独特作用和在不同给药系统中的应用前景。
2)  slow/controlled release
药物缓/控释
3)  drug release
药物缓释
1.
A novel pH-sensitive drug release system was fabricated by coating hydroxypropyl methylcellu-lose phthalate (HPMCP) on a drug-loaded SBA-15 tablet.
以肠溶性包衣材料羟丙基甲基纤维素邻苯二甲酸酯(HPMCP)为原料,在负载法莫替丁(Famo)的SBA-15药片表面包覆HPMCP聚合物膜,成功制备了一种新型的pH敏感药物缓释系统,并考察了此缓释系统在不同pH释放环境中的释放行为。
2.
Chitosan is valuablely developed and applied in medical fields such as tissue engineering scaffold,gene carrier,membrane dialysis,surgical trauma coating material and drug release material for its physiological activity,antibacterial property and blood compatibility.
本文综述了壳聚糖及其以医用为目的的化学改性衍生物在组织工程和药物缓释方面的大量研究成果,从壳聚糖的抑菌机理与血液相容性质的特点出发,探讨对壳聚糖进行血液相容性修饰的理论依据。
4)  drug delivery
药物缓释
1.
In this paper,the research of CPC as drug delivery system has been generally introduced in respects of its physicochemical properties and me.
本文综述了具有药物缓释功能的磷酸钙骨水泥的研究进展,包括材料的理化特性和药物缓释机理的研究。
2.
AIM: To study a novel drug delivery system based on calcium phosphate cement (CPC) in vitro with sodium neproxen (SN) as a model drug.
结果:药物的引入未影响材料的操作性能,该体系的药物缓释符合Higuchi 模型。
3.
Its structure, some physical and chemical nature, showed that ESO-lactide is a very good drug delivery carrier, but some troubles in physical-chemistry property aspects haven’t been solved in the past.
环氧大豆油(Epoxidized soybean oil,ESO )与丙交酯聚合得到的环氧大豆油-丙交酯星形聚合物(ESO-丙交酯,ESO-Lactide)是一种新型生物高分子材料,分子结构中具有较大的包容空间和末端功能团,具有较好的亲水性,可以与许多物质相互作用;从其结构、某些物理与化学性质来看,ESO-丙交酯有望成为一种性能优良的药物缓释载体材料。
5)  sustained drug release
药物缓释
1.
Release rates of the loaded avermectin varied in different dissolving media, and different concentrations of the same dissolving medium would cause different release speeds, which is very important in the study of sustained drug release.
本课题为了改善这种现状,以自制的空心多孔SiO_2纳米球为吸附介质,采用超临界流体技术负载阿维菌素药物,考察了不同共溶剂对这种纳米载体载药量的影响,并初步研究了不同的溶出介质和浓度对药物缓释行为的影响;此外,还研究了淀粉基载体负载药物的各种条件。
6)  controlled release
药物缓释
1.
The preparations of alginate microcapsule,methods of stabilizing the gel and controlling the release rate,and their application in drug controlled release have been discussed.
海藻酸具有相对温和的凝胶条件与良好的生物相容性 ,已广泛应用于药物缓释与生物医学工程。
2.
With a preliminary result of controlled release of BSA as a model drug,it appears that these chemical gels have the potential to be used as.
结果显示:这种基于环糊精自组装形成的超分子水凝胶对于蛋白质药物具有一定的缓释作用, 并且由于麦克加成反应可在人体体温及生理 pH 条件下进行,不需要任何引发剂和催化剂,这种新型水凝胶有望在可注射药物缓释系统中得到应用。
补充资料:控释药物制剂
分子式:
分子量:
CAS号:

性质:简称控释制剂。能使药按要求徐徐释放而以挥更发的疗效,并减轻副作用的剂型。常见的有控释片及胶囊。控释制剂 有发以下几种:(1)肠溶核心型控释片;(2)蚀解型控释片,由药物和阴释剂混合后压制而得;(3)骨架控释片,采用不溶性无毒塑料制成骨架片,随药物徐徐释放,骨架无变化,可随大便排出;(4)膜腔型控释片。

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