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1)  Type I collagen cross-linked telopeptide
Ⅰ型胶原羧基末端肽
2)  procollagen type I ca rboxy-terminal peptide
Ⅰ型前胶原羧基末端肽
3)  ICTP
Ⅰ型胶原交联羧基末端肽
1.
Objective: To evaluate the benefits of using new bone metabolic markers such as urinary pyridinoline cross-linked N-telopeptides of Type I collagen (NTx) and serum pyridinoline cross-linked C-telopeptides of Type I collagen (ICTP) in the detection of bone metastasis in patients with malignant tumors.
目的:探讨溶骨性骨代谢生化指标尿Ⅰ型胶原交联氨基末端肽(NTx)、血Ⅰ型胶原交联羧基末端肽(ICTP)定量检测诊断恶性肿瘤骨转移的价值。
2.
Objective To study the clinical usefulness of determination of serum carboxy terminal telepeptide typeⅠ collagen (ICTP) and aminoterminal prepeptide typeⅠ procollagen (PINP) in cancer patients with bone metastasis for diagnosis and treatment.
目的 :探讨Ⅰ型胶原交联羧基末端肽 (ICTP)和Ⅰ型前胶原氨基端前肽 (PINP)在骨转移Ca中的临床价值。
4)  Carboxyterminal cross-linked telopeptide of type I collagen
Ⅰ型胶原羧基吡啶末端肽
5)  carboxyterminal propeptide of typeⅠprocollagen
Ⅰ型胶原蛋白羧基末端前肽链
1.
【Methods】 Serum IGF-1,osteocalcin(OC),carboxyterminal propeptide of typeⅠprocollagen(PICP),type I collagen cross-linked C-terminal telopeptide(ICTP) were mensurated in 27 cases in ISS children,and compared to 30 cases age-and sex-matched healthy controls.
【方法】测定37例ISS儿童和30例年龄、性别匹配的正常健康儿童的血清IGF-1、骨代谢生化指标骨钙素(OC)、Ⅰ型胶原蛋白羧基末端前肽链(PICP)I、型胶原交联羧基末端肽(ICTP),比较两组水平差异;对IGF-1与骨代谢生化指标、骨龄/年龄比值(BA/CB)和身高标准差得分(HtsDs)之间进行Pearson相关分析。
6)  Carboxyterminal propeptide of type Ⅰ procollagen(PICP)
Ⅰ型前胶原羧基末端前肽
补充资料:前胶原肽酶
分子式:
CAS号:

性质:是存在于细胞外,对前胶原进行加工的酶。它包括两种酶:(1)N-末端前胶原肽酶,其分子量为260 000,能够切除前胶原的氨基前肽;(2)C-末端前胶原肽酶,其分子量为80 000,属于糖蛋白,能切除前胶原的羧基前肽。两种酶均需要二价阳离子,如Ca2+。

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