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1)  TACE antisense oligodeoxyribonucleotide
TACE反义寡核苷酸
1.
The pretreatment with TACE antisense oligodeoxyribonucleotide(TACE A ODN) (5mg/kg weight) or with polyclonal antibody against TNF α.
TACE反义寡核苷酸能有效地抑制mTNF α转化为sTNF α ,使腹腔巨噬细胞表面上的mTNF α表达明显增高 (P <0 。
2)  antisense oligonucleotides
反义寡核苷酸
1.
Stduy on inhibition of proferation of lens epithelial cells by Ccnd1 antisense oligonucleotides liposomes in rats;
Ccnd1反义寡核苷酸脂质体抑制大鼠晶状体上皮细胞增殖的研究
2.
Inhibiting effect of Ccnd1 antisense oligonucleotides liposomes on proliferation of lens epithelial cells after extracapsular lens extraction in rats;
Ccnd1反义寡核苷酸脂质体对囊外摘出术后大鼠晶状体上皮细胞增殖的抑制作用
3.
Inhibitory effects of c-myc antisense oligonucleotides on the proliferation of MKN-45 cells;
c-myc反义寡核苷酸对胃癌MKN-45细胞株增殖的影响
3)  antisense oligodeoxynucleotides
反义寡核苷酸
1.
Effects of Tiam 1 antisense oligodeoxynucleotides transfection on the invasive and migratory potentials of gastric cancer cells in vitro and vivo;
Tiam 1反义寡核苷酸转染对胃癌细胞体内外侵袭转移能力的影响
2.
c-myc antisense oligodeoxynucleotides in reversion of cisplatin resistance in ovarian cancer cell line COC1/DDP;
c-myc反义寡核苷酸对卵巢癌细胞COC1/DDP顺铂耐药的逆转作用
3.
Effects of antisense oligodeoxynucleotides on Nogo-A mRNA expression in injured optic nerves;
反义寡核苷酸抑制大鼠损伤视神经Nogo-A mRNA的表达
4)  Antisense oligodeoxynucleotide
反义寡核苷酸
1.
Effect of antisense oligodeoxynucleotide(ASODN) of survivin gene on inducing apoptosis and chemotherapy sensitivity of Gastric cancer cell;
Survivin反义寡核苷酸诱导胃癌细胞凋亡及对化疗药物的增敏作用
2.
C-myc antisense oligodeoxynucleotide inhibits the growth and induces apoptosis of SW480 cell;
C-myc反义寡核苷酸对结肠癌细胞SW480增殖及凋亡的影响
3.
Inhibitory effect of survivin antisense oligodeoxynucleotides on HepG2 cells by using polyamidoamine dendrimer as gene delivery system;
树形分子递送survivin反义寡核苷酸对HepG2细胞的抑制效应
5)  antisense oligonucleotide
反义寡核苷酸
1.
Effect of STAT3 antisense oligonucleotide and radiotherapy on hep-2 cells cycle;
STAT3反义寡核苷酸联合放疗对喉癌Hep-2细胞周期的影响
2.
Expression of GATA-3 regulated by antisense oligonucleotide and inhaled corticosteroids in an asthma model in mice;
反义寡核苷酸和激素干预对哮喘小鼠GATA-3表达的影响
3.
CD44-specific antisense oligonucleotide on pro-liferation and apoptosis of human trabecular meshwork cells;
CD44反义寡核苷酸对人眼小梁细胞增生与凋亡的影响
6)  P65 antisense oligonucleotids
P65反义寡核苷酸
补充资料:TACE
分子式:C23H21ClO3
分子量:380.86
CAS号:569-57-3

性质:熔点114-116℃,在乙醇中的溶解度0.28g/100ml,在醚中溶解度3.6g/100ml,溶于丙酮、氯仿、四氯化碳和苯,不溶于水。

制备方法:有多种合成路线,由对甲氧基苯乙酮经溴化、成盐、缩合、氯化而得。总收率14.5%;也可由茴香酸出发制备,总收率44.4%,但茴香酸原料价格较贵。以茴香醚为原料,经下列步骤制取泰舒,总收率为21.6%。1.氯代对甲氧基苯乙酮的制备 茴香醚与氯乙酰氯反应得氯代对甲氧基苯乙酮。2.1,1,2-三(对甲氧苯基)乙烯的制备 溴代茴香醚与镁制得格氏试剂,与氯代对甲氧基苯乙酮反应得油状物继续与PTS反应得1,1,2-三(对甲氧苯基)乙烯。3.泰舒的制备 1,1,2-三(对甲氧苯基)乙烯氯化得泰舒。

用途:雌激素类药,主要用于治疗前列腺肿大和妇女更年期综合症。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条