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1)  base-base correlation
碱基对关联性
1.
In order to assist the design of short interfering ribonucleic acids (siRNA), 573 non-redundant siRNAs were collected from published literatures and the relationship between siRNAs sequences and RNA interference (RNAi) effect is analyzed by a support vector machine (SVM) based algorithm relied on a base-base correlation (BBC) feature.
为了辅助siRNA的设计,从已发表文献中共收集到573个siRNA的实验数据,使用基于统计学习理论的支持向量机(SVM)方法,提取了siRNA序列的碱基对关联性(BBC)特征,然后使用十倍交叉验证方法,对siRNA沉默目标基因的效率进行了预测。
2)  base correlation
碱基关联
1.
Two parameters which are designed to describe compositional difference between two DNA sequences and base correlation in DNA sequence are defined,and then the characteristics of variation in composition and base correlation in human processed pseudogenes during evolution are studied.
定义描述DNA序列组分差异性和碱基关联的两个参数,分析了人类加工假基因演化过程中其组分信息和碱基关联信息的变化特征,发现随时间的推移,加工假基因的组分逐步向其侧翼序列漂移,紧邻碱基关联逐步增强。
3)  correlation of double base
双碱基关联
4)  Correction of Triplet
碱基关联三联体
5)  adjacent base correlation
紧邻碱基关联
1.
It is found that:1) the adjacent base correlation gradually strengthens during evolution;2) small k-mer(k=1,2,…,5).
结果发现,1)假基因序列的紧邻碱基关联随进化逐步增强;2)k-mer信息熵中,小k-mer(k=1,2,…,5)信息熵随进化减少,大k-mer(k=7,8)信息熵随进化先迅速减少,随后增加;3)关联信息熵随进化减少,其中紧邻碱基关联信息熵的减少幅度最明显。
6)  symmetry correlation
对称性关联
1.
It has been found in the study of the dissociation process that the dissociation lirnitsmust accord with the directionality rule of symmetry correlation,which correctly determines the dissociationchannels in the various processes of dissociation.
通过对分子离解过程的研究,发现离解极限必须符合对称性关联的方向性原则。
补充资料:碱基对
分子式:
CAS号:

性质: 互补碱基之间通过氢键连接的核苷酸对。A和T结合(在RNA中A和U结合),G和C结合。

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