1) targeting induced local lesion in genome
点突变检测(TILLING)
2) discontinuity detection
突变点检测
3) point mutation detection
点突变检测
1.
Recently,we have developed an electrochemiluminescence-polymerase chain reaction(ECL-PCR) method for point mutation detection.
我们分别将该法用于Presenilin-1基因和H-ras癌基因的点突变检测,结果均可明显区分突变型样品和野生型样品。
5) mutation detection
突变检测
1.
Development of System for Mutation Detection of Autosomal Dominant Polycystic Kidney Disease PKD1 Gene and Its Application in Hans;
汉族人常染色体显性遗传性多囊肾病1型致病基因突变检测体系的建立及应用
2.
Objective To study whether protein truncation test (PTT) is suitable for mutation detection in large size gene,such as ATM .
目的 :研究蛋白质截短技术 (PTT)在ATM等大基因突变检测中的可行性。
3.
We studied a novel mutation detection method of the two Lac Ⅰ target genes in pMCLacⅠ/neo transgenic mice.
实验结果提示 ,M9 L正向选择系统可应用于pMCLacⅠ neo转基因小鼠中两种LacⅠ靶基因的检测 ;实验中所建立的突变检测方法快速、有
6) Mutation analysis
突变检测
1.
Three AD-SPG family members were studied through clinical examinations,and then mutation analysis of the spastin gene was screened by PCR combined with DNA sequencing in the probands of these three AD-SPG pedigrees.
结论:首次在国内应用DHPLC技术对spastin基因进行突变检测;国人SPG患者存在spastin基因无义突变651C→T(p。
补充资料：点突变
点突变
又称为"基因突变"。是指细胞内DNA分子链上某一区段在结构上发生碱基对组成或排列顺序的改变，通常可引起一定的表型变化。基因突变是新基因产生的方式，也是生物进化的重要因素之一，基因突变可以是自发的也可以是诱发的。遗传物质的突变广义上包括染色体畸变，狭义上专指点突变，实际上畸变和点突变的界限并不明确，特别是微细的畸变更是如此。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条