1)  vp2 protein
单抗竞争ELISA
1.
Monoclonal antibodies against FMDV vp2 protein were prepared and a competitive ELISA based on the monoclonal antibodies and vp2 protein was established.
制备AsiaI口蹄疫病毒vp2单克隆抗体(mAb)并建立了单抗竞争ELISA方法。
2)  MAb
单抗
1.
Objective:To prepare the monoclonal antibody(mAb) against human B7 1 and analyse its biological characteristics.
目的 :制备鼠抗人B7 1分子 (mAb)单抗及研究其生物学活性。
2.
Pure fimbriae were verified by Western-blot with monoclonal antibody (Mab) of F107.
用针对F107菌毛的单抗做免疫印迹反应,证实此条带为F107菌毛蛋白。
3)  monoclonal antibody
单抗
1.
Primary identification of the anti-human dendritic cells and antirat dendritic cells monoclonal antibody by flow cytometer;
抗人DC和抗大鼠DC单抗杂交瘤的细胞特异性鉴定
2.
Preparation of Monoclonal Antibody against Shiga-like ToxinⅡ Variant A Subunit;
志贺样毒素II型变异体A亚单位单抗的制备
3.
Objective To explore a preparing method for MRI target contrast agent, dextran magnetite particles coated with CL 3 monoclonal antibody (McAb DMP).
结果 制备的磁性纳米微粒与单抗相比保持了较高的结合活性和免疫活性。
4)  McAb
单抗
1.
The combination between tetra(tera-trimethy lamine benzene) prophyrin and McAb 3B6 resulted in a significantly hyperchromic effect,which indicated rigidity and compactness of the combination,and existence of the aromatic amino acids at the combination sites of antigen in antibody.
 四(4-三甲胺苯)卟啉与单抗体3B6结合后,有显著的增色效应,反映了卟啉与抗体是刚性紧密结合的,抗体的抗原结合部位有芳香族氨基酸存在,并且产生巨大的诱导效应。
2.
Experimental results showed that McAb26C3 did not block the invasion of Shigella into HeLa cells with an increasing number of Shigella F2a in the cells.
采用HeLa细胞入侵及其阻断试验 ,观察抗志贺菌菌膜蛋白和LPS的单抗对志贺菌入侵HeLa细胞的影响。
3.
The results showed that 6 McAb secret high specific antibodies against rBovIFN-γ, and they didn’t react with rCHIFN-γand rCHIL-2.
本研究以纯化的原核表达融合蛋白rHIS-BovIFN-γ免疫BALB/c小鼠,以原核表达融合蛋白rGST-BovIFN-γ为筛选抗原,通过淋巴细胞杂交瘤技术,研制出6株稳定分泌抗牛IFN-γ单克隆抗体的杂交瘤细胞株,分别命名为1C12、4A10、5F5、6E12、2D10、6F6,经初步鉴定,6株单抗均能特异性识别并结合rBovIFN-γ,且不与鸡-γ干扰素、白介素-2发生交叉反应;免疫球蛋白亚类依次为IgG1、IgM、IgM、IgM、IgG2a、IgM,杂交瘤上清间接ELISA效价为1:1600、1:400、1:3200、1:800、1:800、1:1600,腹水效价为1:12800、1:3200、1:25600、1:12800、1:6400、1:12800。
5)  McAbs
单抗
1.
Development of McAbs Against H9 AIV and Establishment of Antigen Capture ELISA for Detecting H9 Avian Influenza Virus;
H9亚型禽流感病毒单抗的制备及其抗原捕获ELISA方法的建立
2.
The McAbs were specific to H9 AIV, and appeared to possess different biological properties in antigen recognization o.
采用血凝抑制(HI)和ELISA方法筛选阳性细胞克隆,连续多次克隆培养后获得3株能稳定分泌H9亚型HA特异性单抗的细胞株1F4C4、9F12D1、2C5H12。
6)  Trastuzumab
曲妥单抗
参考词条
补充资料:竞争性拮抗作用
分子式:
CAS号:

性质:为拮抗剂能和激动剂竞争同一受体而使激动剂作用减弱或消失。如果这类拮抗是可逆的,即增加激动剂剂量,其拮抗作用可被克服,则称为可逆性竞争性拮抗作用(reversible competitive antagonism);如果是不可逆的,即拮抗剂与受体形成螯合牢固的共价键而不易解离,则即使增加激动剂剂量,仍不能克服其拮抗作用,称为不可逆性竞争性拮抗作用(irreversible competitive antagonism)。

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