Comparing with clas-sical T-DNA knock-out mutagenesis technology by the loss-of-function mutation, the activation T-DNA tagging technique based on the gain-of-function mutation has its own particular advantages, mainly characterized by producing dominant mu-tants of genes with functional redundancy and easily cloning of the genes.

The strategies in functional analysis of novel genes include bioinformatic analysis,gene expression profile analysis,gain-of-function/loss-of-function analysis,and protein-protein interaction analysis.

Again on acquired defense functions of organism;

Objective To determine whether intravenous immunoglobulin (IVIG) has clinical effects in adjunctive therapy during infections in adults with acquired immunodeficiencies.