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1)  Human leukemia inhibitory factor
人白血病抑制因子
1.
Objective To establish the eukaryotic expressing cell strains of human leukemia inhibitory factor(hLIF) gene via retrovirus vector.
目的构建逆转录病毒载体介导的人白血病抑制因子(human leukemia inhibitory factor,hLIF)基因真核稳定表达细胞株。
2.
Objective: To construct human embryo fibroblasts cell strain stably expressing human leukemia inhibitory factor(hLIF) or human oncostatin M(hOSM) gene which are supposed to be used as feeder layer cells for the proliferation of umbilical cord blood CD34~+ HSPC in vitro.
目的: 构建稳定表达人白血病抑制因子(leukemia inhibitory factor,LIF)及人抑瘤素M(oncostatin M,OSM)基因的人胚胎成纤维细胞,将其作为饲养层细胞,研究其对脐带血CD34~+造血干/祖细胞(hematopoietic stem/progenitor cells,HSPC)体外扩增的支持作用。
3.
Objective To establish the transgenic cell strains expressing recombinant retroviral vector of human leukemia inhibitory factor (hLIF) gene which was supposed to be used as feeder layer cells for the proliferation of umbilical cord blood CD34+ hematopoietic stem/progenitor cell (HSPC) in vitro.
目的建立转人白血病抑制因子(hLIF)基因逆转录病毒载体的饲养层细胞,并观察其对CD34+造血干/祖细胞(HSPC)的扩增作用。
2)  human leukemia inhibitory factor gene
人白血病抑制因子基因
1.
The termination codon of human leukemia inhibitory factor gene was deleted by PCR mutation, in order to put the gene into the same reading frame together with the myc epitope and 6 × His tag in the expression vector pPICZαA.
用PCR突变的方法使人白血病抑制因子基因的终止密码子缺失,并与质粒pPICZαA上的myc表位及6个组氨酸处于同一读码框,构建融合表达载体pPICZαA-hLIFM。
3)  rh-LIF
重组人白血病抑制因子
1.
The impact of rh-LIF on HL-60 cell line;
重组人白血病抑制因子对HL-60细胞的作用及机制研究
4)  LIF
人白血病抑制因子(LIF)
1.
The expression of LIF and IL-2 in the endometrium at implantation window before and after the management of hydrosalpinx
输卵管积水处理前后窗口期子宫内膜人白血病抑制因子(LIF)和白介素-2(IL-2)的表达
5)  LIF
白血病抑制因子
1.
Study on the expression and clinical significance of LIF and MIF in the tissues of endometrial hyperplasia;
子宫内膜增生组织中白血病抑制因子和巨噬细胞移动抑制因子的检测及临床意义
2.
Relations between leukemia inhibitory factor(LIF) and endometrium on the window of implantation in women;
种植窗期子宫内膜类型和白血病抑制因子的关系
3.
THE DIFFERENTIATION OF HUMAN NEURAL STEM CELLS INTO DOPAMINERGIC NEURONS INDUCED BY IL-1αAND COMBINATION OF IL-1α,IL-11,LIF AND GDNF;
白介素-1α及与白介素-11、白血病抑制因子和胶质细胞源性神经生长因子联合诱导人神经干细胞向多巴胺神经元的分化
6)  leukemia inhibitory factor
白血病抑制因子
1.
The effects and impact of leukemia inhibitory factor on leukemia cells;
白血病抑制因子对白血病细胞的作用及影响
2.
Regulatory effect of dissociative intracytoplasmic domain of leukemia inhibitory factor receptor α subunit on growth of HL-60 cells;
游离的白血病抑制因子受体α亚基胞内功能片段对HL-60细胞的生长调节
3.
Progress in study on embryo implantation regulating mechanism of leukemia inhibitory factor;
白血病抑制因子调节胚胎着床机理的研究
补充资料:白血病抑制因子
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性质:LIF  一种由180个氨基酸组成的糖蛋白,核心蛋白分子量20000,有7个糖基化位点,6个Cys,分子内部二硫键对于维持LIF分子结构和生物活性可能起重要作用。能调节细胞的增殖、分化和表型,抑制脂蛋白脂肪酶活性,促进骨的重吸收,诱导肝脏急性期蛋白的产生。

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