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1)  collagenase 1
胶原酶I
1.
The catalytic domains of two matrix metalloproteinases——collagenase 1 and stromelysin 1 have been studied by means of fluorescence spectroscopy and high hydrostatic pressure.
为了解两种基质金属蛋白酶———成纤维细胞胶原酶I(fibroblastcollagenase 1)和基质酶I(stromelysin 1)的结构异同 ,利用荧光光谱学和高压力方法比较了这两种酶催化区的结构特性。
2)  Collagen I
I型胶原
1.
Effects of Yulangsan polysaccharide on proliferation and collagen I production of hepatic stellate cells;
玉郎伞多糖对肝星状细胞增殖和I型胶原合成的影响
2.
Expression of collagen I, II and alkaline phosphatase in osteogenesis by rhBMP 2 in vivo;
rhBMP-2在体内诱导成骨中I,II型胶原及碱性磷酸酶的表达
3.
Objective : To research the effect of total saponins of panax notoginseng (SPN) on the production of collagen I and TGF-β1 in experimental cirrhosis rats induced by carbon tetrachloride,and to elucidate its possible mechanism.
目的:观察三七总皂甙对肝纤维化大鼠I型胶原及TGF-β1表达的影响,并探讨其抑制肝纤维化的可能机制。
3)  collagen type I
I型胶原
1.
Comparison of the preparation of high purity collagen type I from four biomaterials;
从四种生物原料中制备高纯度I型胶原的比较
2.
Effects of decorin on collagen type I of rat tendon cells and its mRNA expression in vitro;
核心蛋白聚糖对鼠肌腱细胞I型胶原及其mRNA的影响
3.
Expression of collagen type I and II in normal and keratoconus corneas;
I型和II型胶原在正常角膜和圆锥角膜中的表达
4)  collagen type I
胶原I型
5)  collagen I
胶原I
1.
ObjectiveTo develop stable cultures of human vascular endothelial cells(ECs) and smooth muscle cells(SMCs) in order to investigate:(1)effect of ECs conditioned medium(ECCM) on proliferation and collagen I production of SMCs;(2)effect of CyA directly on proliferation and collagen I production of unstimulated SMCs;(3)effect of CyA on proliferation and collagen I production of SMCs treated with ECCM.
01);CyA仅在5001、000 ng/ml时对非刺激下SMCs增殖有显著的抑制作用,而所有浓度的CyA都显著降低胶原I产物的含量,最多降低(24。
6)  type I collagen
I型胶原
1.
SYBR Green I-based real-time quantitative RT-PCR method for detecting mRNA level of type I collagen in rats;
建立SYBRGreen实时RT-PCR定量检测大鼠I型胶原mRNA水平方法
2.
The effects of fluoride on type I collagen in cultured dental papilla cells;
氟对体外培养人牙乳头间充质细胞合成I型胶原的影响
3.
Objective It is to observe the influence of endotoxin on hepatic stellate cell(HSC) proliferation,type I collagen and leptin expression.
采用ELISA法检测其培养48 h时瘦素和I型胶原水平。
补充资料:胶原酶
分子式:
CAS号:

性质: 又称骨胶原酶,简称胶原酶。由溶组织梭菌(Clostridum histolyticum)制取而得。最适pH值7~8。具有独特的消化天然胶原和变性胶原能力。去污剂、六氯环己烷和重金属离子可降低酶活性。专一作用于原胶原,使其断裂进而被其他蛋白酶水解,不水解纤维蛋白,球蛋白。主要局部外用于烧伤,尚可用于治疗溃疡、浓疮、脊椎软骨增生。

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