1) aminoacyl-tRNA synthetase
氨酰tRNA合成酶
1.
The amino acids are transferred to the cognate tRNAs by the aminoacyl-tRNA synthetases, and then involved in the synthesis of the protein.
氨酰tRNA合成酶是生命进化过程中最早出现的一类蛋白质 ,氨酰tRNA合成酶帮助氨基酸转移到相应的tRNA上 ,进而参与蛋白质的合成保证了生命体的严谨性和多样性 。
2) tyrosyl-tRNA synthetase
酪氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
3) glycyl-tRNA synthetase
甘氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
4) alanyl-tRNA synthetase
丙氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
5) aminoacyl-tRNA synthetase
氨基酰-tRNA合成酶
1.
Physiology,pathology and drug design related with editing of aminoacyl-tRNA synthetase;
氨基酰-tRNA合成酶编校相关的生理、病理效应和药物设计
2.
Recent studies show that aminoacyl-tRNA synthetases play important roles in cell life,such as taking part in intracellular RNA degrading,mRNA splicing,gene transcription regulation,immune response and angiogenesis.
氨基酰-tRNA合成酶(ARS)催化特异的氨基酸结合到对应tRNA上,确保mRNA高精度地翻译为蛋白质。
3.
Recent studies showed that some mitochondrial aminoacyl-tRNA synthetases are closely related with human diseases.
氨基酰-tRNA合成酶是一类古老的蛋白质,催化蛋白质生物合成中的第一步反应。
补充资料：氨酰-tRNA合成酶
分子式：
CAS号：
性质：按照下列反应催化氨基酸与特定tRNA相结合的酶。氨基酸+tRNA+ATP→氨酰-tRNA+AMP+ppi这个反应分两步进行。第一步：氨基酸+ATP+酶=酶·氨基酸·cAMP+ppi随后氨酰基转移到tRNA的3′-端腺苷酸残基上。酶·氨基酸·cAMP+ tRNA=氨酰-tRNA+酶+AMP这些合成酶也催化氨酰- tRNA的脱酰作用：氨基- tRNA=氨基酸+ tRNA
CAS号：
性质：按照下列反应催化氨基酸与特定tRNA相结合的酶。氨基酸+tRNA+ATP→氨酰-tRNA+AMP+ppi这个反应分两步进行。第一步：氨基酸+ATP+酶=酶·氨基酸·cAMP+ppi随后氨酰基转移到tRNA的3′-端腺苷酸残基上。酶·氨基酸·cAMP+ tRNA=氨酰-tRNA+酶+AMP这些合成酶也催化氨酰- tRNA的脱酰作用：氨基- tRNA=氨基酸+ tRNA
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条