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1)  cyclopurine nucleoside
环核苷
1.
A novel methodology for preparing O8,5′-cyclopurine nucleoside analogues in one step under microwave irradiation was reported.
报道了在微波辅助下,以水作溶剂,NaOH为碱,碘作为催化剂,一步反应生成环核苷类化合物的简单快速方法,避免了传统的两步以上的合成路线。
2)  Bicyclic nucleosides
双环核苷
3)  Tricyclic nucleosides
三环核苷
4)  cyclic nucleotide
环核苷酸
1.
Alterations of glutamate and cyclic nucleotides in neonatal rat brain after cerebral hypoxic-ischemic injury;
新生大鼠脑缺氧缺血对脑组织谷氨酸及环核苷酸的影响
2.
Gaining and Testing the Activity about Two Kinds of 3 ,5 -Cyclic Nucleotide Phosphodiesterases;
两种3′,5′-环核苷酸磷酸二酯酶的制备及活性测定
3.
The levels of cyclic nucleotide in the brain,heart and lung were assayed by radioimmunoassay.
方法32只大鼠随机分成4组(每组8只):对照组、桔梗组、天王补心丸组、天王补心丸缺桔梗组,采用放射免疫法测定大鼠脑、心、肺组织中环核苷酸(cAMP、cGMP)的含量。
5)  cAMP [英][kæmp]  [美][kæmp]
环核苷酸
1.
Expression of PKA R_(Iα) in gastric cancer cells and effects of 8-Bromo-cAMP on its expression and cells proliferation;
cAMP依赖的蛋白激酶PKAR_(Iα)亚基在胃癌细胞中的表达及8-溴-环核苷酸对其表达及细胞增殖的影响
2.
Effect of Acupuncture and Moxibustion on cAMP Level in Chronic Mild Unpredictable Stressors Depression Rats;
针灸对慢性应激抑郁模型大鼠环核苷酸的影响
6)  cyclic nucleotides
环核苷酸
1.
Objective:To study the effect of Spleen-Stomach Regulating Prescription (SSRP) on cyclic nucleotides (CN) content in the brain of rats suffered from epilepsy.
目的:观察调理脾胃复方对癫痫大鼠脑内环核苷酸(CN)含量的影响。
2.
To explore the function of PDE in canine central nerve, gene expression of 18 PDE subtypes in different fractions of canine central nerve(cerebrum,cerebellum,myelencephalon and spinal cord) were detected by RT-PCR,and PDE activity was calculated by the content changes of cyclic nucleotides before and after the PDE reaction examined by high performance liquid chromatography.
为探明磷酸二酯酶(phosphodiesterase,PDE)在犬中枢神经活动中的作用,采用反转录聚合酶链反应检测18个PDE亚型在犬中枢神经不同部位中(大脑、小脑、延髓和脊髓各段)的表达分布,以高效液相色谱法检测环核苷酸在酶反应前后的含量变化,计算PDE活性。
3.
Based on physical and chemical properties of cyclic nucleotydes and the speciality of milk,cyclic nucleotides in milk were extracted with enzyme method.
根据环核苷酸理化性质及乳的特点,采用酶法从乳汁中提取环核苷酸。
补充资料:盐酸环胞苷 ,安西他宾,环胞苷 ,安西他滨
药物名称:安西他滨

英文名:Ancitabine

别名: 环胞啶;环胞甙;盐酸环胞苷 ,安西他宾,环胞苷 ,安西他滨
外文名:Ancitabine ,Cyclocytidine
适应症:
1.对各类急性白血病有效; 2.脑膜白血病有良效; 3.与其他类药物合用治疗实体瘤; 4.眼科用于治疗单皰角膜炎。
用量用法:
1.静滴:成人每次200~600mg(每千克体重4~12mg),溶于5%葡萄糖液或等渗盐水注射液500ml中滴注,每日1次,连用5~10日为1疗程。 2.肌注及口服:剂量同静脉注射。 3.鞘内注射:用于脑膜白血病,成人50~100mg溶于等渗盐水注射液2ml中,每日或隔日1次。 4.滴眼:每1~2小时滴眼1次,或用眼膏,每日涂药4~6次。
注意事项:
1.胃肠道反应有食欲减退、恶心、呕吐、腹泻、口腔炎、口腔溃疡。 2.骨髓抑制:致使白细胞和血小板下降,严重者可有全血象抑制。 3.少数病人有肝功能损害,可出现黄疸;敏感病人可有血尿酸过高、尿酸结晶尿及肾功能障碍。 4.可见体位性低血压;偶有腮腺肿胀、转氨酶增高。 5.肝功能不良者及孕妇慎用。
规格: 针剂环胞甘:每支50mg、100mg、200mg。 片剂:每片100mg。滴眼剂,眼膏:5mg/10ml.



类别:眼科用药
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