1) DNA oxidative damage
DNA氧化性损伤
1.
Many studies showed that natural polyphenols can rapidly repair DNA oxidative damage in chemical system.
我室曾证明多酚类化合物在化学体系中可以非酶性快速修复DNA氧化性损伤,但至今不明此种修复是否也存在于细胞中。
2) oxidative DNA damage
氧化性DNA损伤
1.
Sodium ferulate protects against ischemia-reperfusion induced oxidative DNA damage in rat brain;
阿魏酸钠对大鼠脑缺血-再灌流后氧化性DNA损伤的保护作用
2.
Objective To compare cytotoxic effects of microcystin-LR(MCLR) on human hepatoma cell lines HT17 and HepG2,and then study the oxidative DNA damages induced by MCLR.
目的比较微囊藻毒素-LR(MCLR)对2种人肝癌细胞系HT17和HepG2的细胞毒性差异,研究MCLR对HT17细胞的氧化性DNA损伤作用。
3.
The extractable organic matter of PM10 exerts DNA damage effects in HepG2 cells probably through oxidative DNA damage induced by intracellular ROS,increase of 8-OHdG formation and the expression of NF-κB p65.
结论PM10有机提取物可引起体外HepG2细胞DNA链断裂;DNA链断裂水平随不同季节和不同监测点而异;PM10引起DNA损伤的机制可能是细胞内ROS生成增多,8-OHdG表达增高及NF-κBp65蛋白表达水平升高而导致的氧化性DNA损伤。
3) DNA oxidative damage
DNA氧化损伤
1.
Study on the expression of DNA oxidative damage related repair gene hOGG1 and MGMT in lung cancer cells;
DNA氧化损伤修复相关基因hOGG1、MGMT在肺癌细胞中表达研究
2.
Establishment of DNA oxidative damage model in colorectal crypt cells by hydrogen peroxide;
过氧化氢诱导肠上皮干细胞DNA氧化损伤模型的建立
3.
But the detailed mechanism still remains unclear, and the degree of DNA oxidative damage in ESRD patients has not been well examined.
目的通过检测终末期肾病(ESRD)患者血清中的DNA氧化损伤标志物8-羟基脱氧鸟苷(8-OHdG)含量,探讨ESRD患者中DNA氧化损伤的程度及其影响因素。
4) DNA damage
DNA氧化损伤
1.
Objective The genotoxicity and its molecular mechanism of diesel oil vehicle exhaust were discussed through analysing the oxidative DNA damage induced by exhaust components.
方法 以DNA加合物 8-羟基脱氧乌苷 (8-OHdG)作为DNA氧化损伤的生物学标志物 ,用高压液相色谱 -电化学 (HPLC -EC)法对染毒后的DNA中 8-OHdG进行定量检测 ,通过气质联用法 (GC -MS)进行有机成分分析和原子吸收法 (AAS)对其进行无机元素分析 ,并从化学组成成分的角度探讨DNA分子生物氧化的分子机理。
2.
The oxidative DNA damage of peripheral lymphocytes induced by H_2O_2 was analyzed by SCGE.
1%;松节藻提取物25 mg/kg剂量组对10μmol/L的H2O2诱导的DNA氧化损伤有保护作用,且血浆SOD活性增强,MDA含量下降。
3.
Influence of vitamin A intake of different dosage on DNA damage in rats;
采用单细胞凝胶电泳法 (SCGE)分析比较不同组之间淋巴细胞DNA氧化损伤 ;用高效毛细管电泳法测定尿中O6-甲基鸟嘌呤 (O6-Methyl-guanine ,O6-MeG)的排出量。
5) Oxidative DNA Damage
DNA氧化损伤
1.
BACKGROUND AND AIM:To study the variation of the level of reactive oxygen species(ROS),oxidative DNA damage and antioxidative ability between Pten+/+MEFs and Pten-/-MEFs cells.
背景与目的:研究PTEN缺失细胞中活性氧(ROS)水平、DNA氧化损伤和抗氧化能力的变化。
2.
Objective: To investigate the effect of Mg 2+ on oxidative DNA damage of cultured human umbilical vein endothelial cells.
目的 : 观察 Mg2 + 对 H2 O2 诱导的人脐静脉内皮细胞 DNA氧化损伤的影响。
3.
Objective:To study the variation of levels of antioxidative ability,reactive oxygen species(ROS),lipid perox- idation and oxidative DNA damage between Pten~(+/+)mouse embryonic fibroblasts(MEFs)and Pten~(-/-)MEFs.
目的:研究Pten缺失后小鼠胚胎成纤维细胞抗氧化能力、细胞内活性氧(reactive oxygen species,ROS)水平、脂质以及DNA氧化损伤水平的变化。
6) oxidative DNA damage
氧化DNA损伤
1.
Experimental study on oxidative DNA damage after focal infarction induced by nNOS in brain;
nNOS介导小鼠局灶性脑梗死后氧化DNA损伤的机制研究
补充资料：氧化性
非金属性指原子在化学反应中吸收电子能力。吸收电子能力越强的原子其非金属性也就越强；吸收电子能力越弱的原子其非金属性也就越弱，而其金属性就越强。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条