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1)  surface-enhanced laser desorption and ionization time-of-flight mass spectrometry
表面增强激光解析/电离-飞行时间质谱
2)  SELDI-TOF-MS
表面增强激光解析电离飞行时间质谱
1.
coli were analyzed by Surface enhanced laser desorption/ionization time-of-flight mass spectra(SELDI-TOF-MS),and the data was collected by Ciphe.
蛋白提取液提取细菌蛋白,干化学法测蛋白浓度,应用表面增强激光解析电离飞行时间质谱技术(SELDI-TOF-MS)检测E。
2.
【Objective】To develop a novel and reliable method for diagnosis of pancreatic cancer by surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS).
目的采用表面增强激光解析电离飞行时间质谱(SELDI-TOF-MS)技术检测血清蛋白指纹图,通过差异蛋白组学筛选胰腺癌特有的蛋白标记物,为研究胰腺癌的病理过程和实验诊断奠定基础。
3.
Surface-enhanced laser desorption ionization time of flight mass spectrometry(SELDI-TOF-MS)technique is a high-throughput proteomics approach with simple operation,high sensitivity and marked specificity,and becomes a variety of tumor markers screening analysis platform based on the protein chips combined with mass spectrometry.
表面增强激光解析电离飞行时间质谱技术是一种操作简单、敏感性高、特异性强的高通量蛋白组学方法,是基于蛋白质芯片和质谱技术联用的多种肿瘤标志物筛选的分析平台。
3)  SELDI TOF-MS
表面增强激光解析/电离飞行时间质谱
1.
We have found SELDI profiling in sera of patients with gastric cancer and benign gastric lesion compared to normal volunteers by SELDI TOF-MS and IMAC30 Cu~(2+) proteinchip.
本课题从血清蛋白质组分析入手,利用表面增强激光解析/电离飞行时间质谱和IMAC30 Cu~(2+)固定金属亲合捕获蛋白芯片获得胃癌、良性胃病、正常人的SELDI质谱图,从中发现各个组之间的差异蛋白并建立决策树模型,用以对胃癌的诊断和预后判断,交叉验证和盲法检测结果表明所建立的分类决策树模型具有较高的准确性。
4)  SELDI-TOF-MS
表面增强激光解吸电离-飞行时间质谱
1.
Application of SELDI-TOF-MS technology analyzing serum protein profiling in diagnosis of thyroid cancer;
表面增强激光解吸电离-飞行时间质谱在甲状腺癌诊断及临床分期中的应用
5)  SELDI-TOF-MS
表面增强激光解吸电离飞行时间质谱
1.
Objective:To detect the serum proteomic patterns in lung cancer by surface enhanced laser desorption/ ionization-time of flight-mass spectrometry (SELDI-TOF-MS) protein chip array techniques,screen biomarkers of lung cancer and build diagnostic models in order to evaluate their clinical significance.
目的:探讨用表面增强激光解吸电离飞行时间质谱(SELDI-TOF-MS)技术筛查肺癌血清特异性蛋白质的临床意义。
2.
The proteins were analyzed by surface enhanced laser desorption/ionization time-of-flight mass spectra(SELDI-TOF-MS),compared with other bacteria,and the data was collected by Ciphergen Protein Chip software.
方法选取分枝杆菌标准菌株,提取细菌蛋白,干化学法测蛋白浓度,应用表面增强激光解吸电离飞行时间质谱技术(SELDI-TOF-MS)检测分枝杆菌蛋白表达,和非分枝杆菌蛋白指纹图谱比较,筛选分枝杆菌特征性蛋白。
3.
Methods The Surface enhanced laser desorption/ionization time-of-flight mass spectrometry(SELDI-TOF-MS) and CM10 ProteinChip technology were used to analyze the serum proteins spectrum in 33 cases of AFP-negative PHC, 35 cases of healthy people, 30 cases of AFP-negative CLD, 28 cases of low AFP level PHC and 34 cases of low AFP level CLD.
方法:运用表面增强激光解吸电离飞行时间质谱(SELDI-TOF-MS)技术,选择弱阳离子交换芯片(CM10),检测33例AFP阴性肝癌患者与35例健康人/30例AFP阴性慢性肝病患者、28例AFP低浓度阳性肝癌患者与34例AFP低浓度阳性慢性肝病患者的血清蛋白表达谱,并用Ciphergen ProteinChip Software 3。
6)  Surface enhanced laser desorption ionization time-of-flight mass spectrometry
表面增强的激光解析电离飞行时间质谱
补充资料:基质辅助激光解吸时间飞行质谱
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CAS号:

性质:从原理上讲,它属于激光解吸质谱(LDMS),它与普通LDMS的不同在于,激光不是直接打在试样上使之解吸,而是把试样悬浮在基质中,激光打在基质上,基质吸收并传递激光能量,使基质中的试样解吸出来,试样解吸并电离后进入时间飞行质谱仪中检测。MALDI-TOFMS由于使用了基质辅助,它对激光能量的限制就比较宽了,对不同的试样,改变基质,可以获得更满意的结果。目前MALDI-TOF MS是用来进行药物、生物分子的测定的较好手段。

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