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1)  temozolomide analogues
替莫唑胺类似物
1.
On the base of the characteristics and the physiochemical properties of novel antitumor drug temozolomide, seventeen temozolomide analogues were designed and synthesized, including eight 3-methyl-4-oxoimidazo[5,l-d][l,2,3,5]tetrazine-8-carboxylates (Ia-Ih) and nine 3-methyl-4-oxoimidazo[5,1-d.
针对抗癌新药替莫唑胺的作用特点和理化性质,以替莫唑胺及其活性代谢物3-甲基-4-氧代咪唑[5,1-d][1,2,3,5]四嗪-8-羧酸(Ⅲ)为先导化合物,设计合成了17个替莫唑胺类似物,其中8个3-甲基-4-氧代咪唑[5,1-d][1,2,3,5]四嗪-8-羧酸酯类化合物(Ia~Ih),9个3-甲基-4-氧代咪唑[5,1-d][1,2,3,5]四嗪-8-酰胺类化合物(Ⅱa~Ⅱi),均为未见文献报道的新化合物。
2)  temozolomide
替莫唑胺
1.
Effects of temozolomide capsules in treatment of 31 Chinese patients with malignant gliomas;
替莫唑胺治疗国人恶性脑胶质瘤:31例临床疗效分析
2.
Evaluation of the Efficacy of Radiotherapy Concurrent Temozolomide Chemotherapyin Patients with Brain Metastases;
放疗同步口服替莫唑胺治疗颅内转移瘤疗效评价
3.
Clinical Observation in Temozolomide Combined with Radiotherapy in Treatment of Postoperative Malignant Glioma;
恶性胶质瘤术后应用替莫唑胺化疗联合放疗的临床观察
3)  Temozolomide (TMZ)
替莫唑胺(TMZ)
4)  temozolomide hexyl ester
替莫唑胺酯
1.
Objective: To develop a method so as to determine the related substances in the temozolomide hexyl ester.
目的:建立替莫唑胺酯中有关物质的测定方法。
5)  Polylactic acid temozolomide
聚乳酸-替莫唑胺
6)  temozolomide delayed release microspheres
替莫唑胺缓释微球
1.
PartⅠObservation of tumor inhibitory effect of temozolomide delayed release microspheres on human glioma cell line SHG-44 in vitroObjective:To observe the inhibitory effect of temozolomide delayed release microspheres on human glioma cell line SHG-44 in vitro.
第一部分替莫唑胺缓释微球对胶质瘤细胞系SHG-44体外抑瘤效应的观察目的:观察替莫唑胺缓释微球在体外对SHG-44人脑胶质瘤细胞系的抑制效应。
补充资料:替莫唑胺
分子式:C6H6N6O2
分子量:暂无
CAS号:85622-93-1

性质:暂无

制备方法:暂无

用途:抗肿瘤药

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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