In the article,we reported that Eathworm Fibronolysin showed Rabbits Thrombusolysis strongly and protection of Rat Brain Deficit Oxygen obviously.

Study on the separation and purification of earthworm fibrinolytic enzyme;

Gene Expression of Earthworm Fibrinolytic Enzyme in E.coli, Purification and Bioassay;

Polymorphism of the earthworm fibrinolytic enzyme P-Ⅲ gene in Eisenia fetida;

In Silico Cloning of Component F-I-0 Gene of Earthworm Fibrinolytic Enzymes;

5 phosphate buffer solution was treated with 5 mL 1% glutaraldehyde solution at 25 ℃ for 8 h,then 13 U earthworm fibrinolytic enzymes solution were added into after rinsing the chitosan thoroughly and adsorbed on the carrier at 4 ℃ for 6 h,after rinsing the unimmobilized enzymes with 1 mol/L NaCl,the enzyme activity r.

Then earthworm fibrinolytic enzymes was prepared.

The inflammation started to alleviate,three hours after using EFEG(earthworm fibrinolytic enzyme gel),and disappeared obviously six hours later.

In order to study the effect of bimastos thrombolytic enzyme (BTE) on the cerebral neurocytes the growth processes of the cerebral neurons of embryo Wistar rats were observed from the Ist day to 30th day with different dosages of BTE by cell culture in vitro.