1) Acute Toxicity
经口急性毒性实验
2) Acute oral tox-hty test
经口急性毒性试验
4) Acute oral toxicity
急性经口毒性
1.
BACKGROUND & AIM:To determine the acute oral toxicity and genetic toxicity of ethanol extracts from Momordica charantia(MC),so as to provide experimental basis for its exploitation.
背景与目的:了解苦瓜醇提取物的急性经口毒性和遗传毒性,为苦瓜提取物的食用、药用安全性提供实验依据。
2.
Methods Maximal tolerance test was used to assess acute oral toxicity;methyl thiazolyl tetrazolium(MTT) test,neutral red intake test and clone-forming test were used to assess cytotoxicity;micronucleus test of bone marrow cell,Ames test,mouse lymphoma TK gene mutation assay and comet assay were used to assess genotoxicity.
方法急性经口毒性评价采用最大耐受量法,细胞毒性评价采用噻唑蓝(MTT法)、中性红吸收法(NPI法)和集落形成法,遗传毒性评价采用小鼠骨髓嗜多染红细胞微核试验、Ames试验、小鼠淋巴细胞杀伤细胞(TK)基因突变试验和彗星试验。
3.
The short-term risks of pesticides to avian currently are assessed by comparing the LD50 and LC50 determined from the laboratory acute oral toxicity test and dietary toxicity test.
运用一次性经口染毒法测定了95%二嗪磷原药、50%二嗪磷乳油、10%二嗪磷颗粒剂对鹌鹑、鹧鸪的急性经口毒性,同时运用饲喂法测定了50%二嗪磷乳油对鹌鹑和鹧鸪的急性饲喂毒性。
5) acute toxicity test
急性毒性实验
1.
Methods Acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice,sperm shape abnormality test of mice,thirty day feeding study were.
方法小鼠急性毒性实验、Ames实验、小鼠骨髓嗜多染红细胞微核实验、小鼠精子畸形实验、大鼠30d喂养实验。
2.
Kunming mice were used in the acute and subacute toxicity tests by intragastric administration of Magnolia biondii Pamp volatile oil nanometer bangosome with different dosage and different time, and SD rats were used in the nasal membrane local toxicity test by nose dropping, while.
方法以昆明种小鼠和SD大鼠为实验对象,辛夷挥发油纳米脂质体通过对小鼠不同剂量和时间灌胃给药,进行急性和亚急性毒性实验;大鼠则经滴鼻给药进行鼻黏膜局部毒性实验。
3.
Methods Acute toxicity test was conducted according to GB-15193-94.
结果急性毒性实验,南瓜脱糖发酵滤液20 ml/kg体重剂量组和对照组,雌、雄小鼠均未见明显症状和体征,也无死亡。
6) Acute toxicity
急性毒性实验
1.
Objective To investigate the in vivo anticancer activity and acute toxicity of bisethanolamine salt of cholest-4-en-3β,6β-diol bishemisuccinate(EBCD)and its effects on peripheral hemogram and nucleated marrow cell population in mice.
急性毒性实验按常规方法进行。
2.
Acute toxicity and subacute toxicity of the potassium salt of the anion siw11 Ohave been studied.
本文报道11-硅钨杂多酸钾盐的急性毒性实验和亚急性毒性实验，结果表明该化合物为中等毒性物质。
3.
Results Acute toxicity experiment showed that LD50 of NHFLE was 28.
结论急性毒性实验证实该药毒性低,临床应用安全性好。
补充资料：急性经口毒性
分子式：
CAS号：
性质： 一次经口腔给药摄入体内而使动物中毒至死亡时的药物剂量，以及中毒反应、症状。通常以半数致死量——即LD50 (mg/kg)——来表示。是衡量药物(特别是农药，包括杀鼠剂)急性经口毒性大小的重要指标之一。也是衡量杀鼠剂优劣的重要指标之一。
CAS号：
性质： 一次经口腔给药摄入体内而使动物中毒至死亡时的药物剂量，以及中毒反应、症状。通常以半数致死量——即LD50 (mg/kg)——来表示。是衡量药物(特别是农药，包括杀鼠剂)急性经口毒性大小的重要指标之一。也是衡量杀鼠剂优劣的重要指标之一。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条