1)  Aβdeposition
Aβ沉积
2)  Aβ
1.
Expression of _(1-42) and cerebral protective effects of grape proanthocyanidins in rats during chronic cerebral ischemia;
慢性脑缺血大鼠脑内Aβ_(1-42)表达及葡多酚的脑保护作用
2.
Effect of autoantibodies to on plasma level of in patients with Alzheimer s disease;
阿尔茨海默病自身抗Aβ抗体对血浆Aβ水平的影响
3.
The Neurotoxicity of Glutamate and to Cortex Neurons of Mice;
谷氨酸与Aβ对小鼠大脑层层细胞毒性的研究
3)  Aβ_(25-35)
Aβ_(25-35)
1.
Effects of Xanthoceraside on Learning and Memory Impairment in Mice Induced by Aβ_(25-35);
文冠果壳苷对侧脑室注射Aβ_(25-35)小鼠学习记忆障碍的改善作用及其机制研究
2.
The Effects of Ginsenoside Rg1 on the Cell Models Induced by H_2O_2 and Aβ_(25-35) in Patients with Alzheimer s Disease;
人参皂苷Rg1对H_2O_2和Aβ_(25-35)诱导的ALZHEIMER细胞模型作用的研究
3.
The Protective Effects of Cyclophilin A on Injury of PC12 Cells Induced by Aβ_(25-35);
亲环素A对Aβ_(25-35)诱导PC12细胞损伤的保护作用
4)  β-amyloid peptide(Aβ)
Aβ肽
1.
Alzheimer s disease(AD) is characterized pathologically by the deposition of amyloid,the major component of which is a 40-42 residue peptide known as the β-amyloid peptide(Aβ).
铜锌等过渡金属离子与Aβ肽的沉积直接相关,研究这些金属离子与Aβ肽的作用对理解老年痴呆症的病理过程并开发相应的治疗药物至关重要。
5)  Aβ_(1-42)
Aβ_(1-42)
1.
Effects of Xanthoceraside on Learning and Memory Impairment in Mice Induced by i.c.v. Aβ_(1-42);
文冠果壳苷对侧脑室注射Aβ_(1-42)致痴呆模型小鼠学习记忆障碍的改善作用
6)  Aβ[31-35]
Aβ[31-35]
1.
Activation of group Ⅲ mGluRs attenuates neuron apoptosis induced by Aβ[31-35];
激活第Ⅲ组代谢型谷氨酸受体拮抗Aβ[31-35]诱导的神经元凋亡
参考词条
补充资料:1-[β,β,β-三(对氯苯基)丙酰]-4-甲基哌嗪
分子式:C26H25CL3N2O
分子量:487.85
CAS号:2390-22-9

性质:该品溶点213-215℃。作兽用驱虫药时常用基盐,又称Dieroden。盐酸盐的熔点为267-269℃,易溶于热水和醇。

制备方法:以三(对氯苯基)甲醇(Ⅰ)为原料,与氰乙酸加成得β,β,β-三(对氯苯基)丙腈(Ⅱ),经浓硫酸水解得β,β,β-三(对氯苯基)丙酸(Ⅲ),再用五氯化磷酰氯化,得到β,β,β-三(对氯苯基)丙酰氯(Ⅳ),最后与N-甲基哌嗪缩合制得海涛林。

用途:该品为治疗牛、羊矛形腔吸虫病的高效药物,具有作用强、驱虫率高(96%以上)、毒性低、适口性好等优点,国外畜牧业应用十分广泛。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。