Investigation in Synthesis of Dane Salt from D-p-hydroxyphenylglycine which is Produced in Enzymatic Process;

Determination of D-p-hydroxyphenylglycine by HPCE;

Screening and study of bacterial strains producing D-p-hydroxyphenylglycine;

The activity of the strain for producing Hydantoinase was improved,which is of very important significance to D-P-hydroxyphenyl glycine,the middle product of β-lactam antibiotics.

It is a potential method for the production of D-hydroxyphenylglycine by enzymatic synthesis.

D-hydroxyphenylglycine(D-pHPG) was the most important precursor used for the synthesis of Semisynthetic penicillin and cephalospor and was a produce competed furiously in the field of pharmacy.