1) indirect acting mutagen
间接致突物
2) directly acting mutagen
直接致突物
3) Direct acting mutagens
直接致突变物
4) indirect carcinogen
间接致癌物
1.
The immortal L02 and pre-transformation stage L02-R cells were treated with the representative indirect carcinogen aflatoxin B1 (AFB1), under three in vitro metabolic activation systems: overexpression metabolic enzyme P450 CYP1A2, low-dose substrate induction, and the metabolic auxiliary system added with classic rat S9.
选择具有代表性的间接致癌物黄曲霉毒素B1(aflatoxin B1,AFB1)作用于永生化和转化前期细胞株,采用三种代谢系统:高表达代谢酶P450 CYP1A2,低剂量底物诱导和加入经典的大鼠S9代谢辅助系统,通过软琼脂克隆形成试验和裸鼠皮下成瘤试验来比较在不同的代谢活化系统下,间接致癌物诱导细胞转化的效能。
5) indirect-acting carcinogen
间接致癌物;间接致癌原
6) mutagens
致突变物
1.
Removal of organic substances and Ames mutagens from drinking water using both O_3 + AC and membranes process;
饮用水中有机物和Ames致突变物的去除
2.
Expermental results of the effect and mechanism of removing TOC and Ames mutagens from drinking water using AC NF process showed that the adsorptive ability of AC was limited,depending on the characters of AC and the organic matters in drinking water.
分别以地表水和地下水为水源的水厂出水为研究对象 ,探讨活性炭 纳滤膜工艺对饮用水中总有机碳和Ames致突变物的去除效果及机理 。
3.
The source water and effluents of five kinds of water purification process were studied by Ames tests,the results show that bioceramic can remove direct mutagens partly,and decline the MR value of the raw water.
具有生物陶粒及活性炭吸附单元的Ｂ、Ｃ、Ｅ流程，对去除水中直接致突变物最为有效，使ＴＡ９８及ＴＡ１００菌株在各试验剂量下的ＭＲ比值均小于２。
补充资料：间接致突物
分子式：
CAS号：
性质：大多数致突变的化学物质在体外并不直接具有致突变性，都需要经过体内的生物转化，才能发挥其致突变作用。这种活化作用依赖于体内微粒体非特异功能氧化酶系而完成的。
CAS号：
性质：大多数致突变的化学物质在体外并不直接具有致突变性，都需要经过体内的生物转化，才能发挥其致突变作用。这种活化作用依赖于体内微粒体非特异功能氧化酶系而完成的。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条