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1)  diltiazem
硫氮 酮
2)  Diltiazem
硫氮卓酮
1.
A Clinical Investigation of Diltiazem s Effects on Renal Function in Undergoing Cardiopulmonary Bypass;
硫氮卓酮对体外循环后肾功能影响的临床研究
2.
Diltiazem 1 μg·kg-1·min-1(group Ⅰ)or 2 μg·kg-1·min-1(group Ⅱ)were pumped respectively from the beginning of operation to the end of CPB.
目的观察钙通道阻断药硫氮卓酮对心内直视手术瓣膜置换术中心肌肌钙蛋白I(cTnI)、超氧化物歧化酶(SOD)、丙二醛(MAD)及血清可溶性粘附分子(sICAM-1)的影响,探讨其对心肌的保护作用。
3.
Objective Objective To investigate the effects of diltiazem on renal function in patients who underwent cardiopulmonary bypass.
目的探讨硫氮卓酮对体外循环心脏手术后肾功能的影响。
3)  diltiazem
硫氮唑酮
1.
Effects of Long-term Use of Diltiazem on the Dosage of Ciclosporin A and Renal Function of Patients after Renal Transplantation;
肾移植术后长期应用硫氮唑酮对环孢素A用量和肾功能的影响
2.
The Experimental Study on Electrophysiologic Mechanisms Responsible for Ischemia and Reperfusion Arrhythmias and the Effective Mechanisms of Diltiazem;
缺血-再灌注性心律失常电生理机制及硫氮唑酮对其作用机理的实验研究
3.
Objective: To evaluate the therapeutic effect of tongxinluo, a Chinese medicine, in comparison of diltiazem in patients with X - syndrome.
目的:比较通心络胶囊与硫氮唑酮治疗心脏X综合征的临床疗效。
4)  Diltiazem
硫氮酮
1.
Diltiazem Effects on Left Ventricular Early Diastolic Flow Propagation Velocity in Patients with Hypertrophic Cardiomyopathy;
硫氮酮对肥厚型心肌病患者左心室舒张早期血流传播速度的影响
2.
The Therapeutic Effect on Chronic Corpulmonale in Acute Aggravating Period with Sodium Tanshinone Sulphonate ⅡA and Diltiazem;
丹参酮ⅡA磺酸钠联合硫氮酮治疗肺心病急性加重期的疗效分析
3.
Method:60 patients with X-syndrome from January 2003 to May 2007were diveded into two groups:30 patients treated with heart-protecting musk pill and thirty patients treated with diltiazem.
目的:比较麝香保心丸与硫氮酮治疗心脏 X 综合征的临床疗效。
5)  Diltiazem ER
硫氮酮缓释剂
6)  Rubeanic acid
氮丙啶二硫酮
补充资料:硫氮卓酮
分子式:C22H26N2O4S·HCl
分子量:450.98
CAS号:33286-22-5

性质:白色结晶或结晶性粉末。熔点187-188℃。易溶于水、甲醇、氯仿,难溶于无水乙醇,不溶于苯。无臭,味苦。

制备方法:由2-氨基硫酚与对甲氧苯基环氧丙酸乙酯缩合得2-(4-甲氧基苯基)-3-羟基-1,5-苯并硫氮杂 -4(5H)-酮。再经酰化、与二甲氨基氯乙烷缩合、成盐制得硫氮卓酮。

用途:钙通道阻滞药,用于室上性心律失常、心绞痛、老年人高血压等。本品为冠脉扩张药,对心绞痛有效。用于运动性绞痛及陈旧性心肌梗塞引起的心绞痛治疗。本品对雌小鼠口服LD50为640毫克/公斤,雄大鼠口服LD50为560毫克/公斤。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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