1) nonpolyposis hereditarycolon cancer (NP-HCC)
非息肉病性遗传性结肠癌
2) HNPCC
遗传性非息肉型结肠癌
3) Hereditary nonpolyposis colorectal cancer
遗传性非息肉病性结直肠癌
1.
Hereditary nonpolyposis colorectal cancer:an analysis of 11 kindreds.;
遗传性非息肉病性结直肠癌11家系临床病理分析
2.
Clinical and pathological analysis of 8 hereditary nonpolyposis colorectal cancer pedigrees
遗传性非息肉病性结直肠癌8个家系临床及病理分析
3.
Objective To gain an insight into the large intragenic hMSH2 and hMLH1 deletions in Chinese hereditary nonpolyposis colorectal cancer(HNPCC)families.
目的了解中国人遗传性非息肉病性结直肠癌(HNPCC)家系hMSH2和hMLH1基因大片段缺失特点。
4) hereditary non-polyposis colorectal cancer
遗传性非息肉性大肠癌
5) Hereditary non-polyposis colorectal cancer
遗传性非息肉病性大肠癌
1.
Hereditary non-polyposis colorectal cancer (HNPCC),also called Lynch syndrome,is an autosomal-dominantly inherited disease and is associated with germline mutations in mismatch repair(MMR)genes and microsatellite instability(MSI).
遗传性非息肉病性大肠癌(HNPCC)是一种由错配修复基因(MMR)突变造成的常染色体显性遗传病,又称Lynch综合征,是遗传性大肠癌的代表。
2.
Objective To investigate the relationship between microsatellite instability(MSI) and the expression of transforming growth factor β receptor II(TGFβRII),mismatch repaire(MMR) proteins in Hereditary Non-polyposis Colorectal Cancer(HNPCC).
目的观察遗传性非息肉病性大肠癌(HNPCC)和大肠腺瘤癌组织中TGFβRII、错配修复基因(hMLH1、hMSH2、hMSH6)蛋白表达和微卫星不稳定(MSI)的关系。
6) Hereditary nonpolyposis colorectal cancer
遗传性非息肉病性大肠癌
1.
Clinical characteristic,diagnosis and therapy of hereditary nonpolyposis colorectal cancer in 32 cases of 11 families;
遗传性非息肉病性大肠癌11个家系32例的临床特点与诊治
2.
Background and ObjectivesHereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal and dominantly inherited cancer predisposition caused by a constitutional defect in a mismatch repair (MMR) gene, with a disease penetrance that approaches 80-90%.
研究背景与目的 遗传性非息肉病性大肠癌(HNPCC)是由于DNA错配修复基因(MMR)发生胚系突变所致的一种单基因显性遗传性疾病,占所有结直肠癌的5%-15%,外显率达80%-90%,多见于青年患者(年龄≤40岁)。
补充资料：遗传分型
分子式：
CAS号：
性质：利用限制性片段长度子态性对某些基因(如人白细胞抗原基因)进行分型。
CAS号：
性质：利用限制性片段长度子态性对某些基因(如人白细胞抗原基因)进行分型。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条